Unification of independent collection of transcription factor binding sites and motifs. YeasTracthttp://www.yeastract.com/ Yeast-specific database. Factors, binding sites and motifs + tools. FlyReghttp://www.flyreg.org/ Drosophila DNase I Footprint Data...
Transcription factor binding site maps Position frequency matrices (PFMs) of transcription factors were derived from JASPAR (release 2022) for the non-redundant CORE vertebrate collection (http://jaspar.genereg.net/download/CORE/JASPAR2022_CORE_vertebrates_non-redundant_pfms_meme.zip)20 and motif scan...
Transcription factors (TFs) are key cellular components that control gene expression. They recognize specific DNA sequences, the TF binding sites (TFBSs), and thus are targeted to specific regions of the genome where they can recruit transcriptional co-factors and/or chromatin regulators to fine-...
Transcription factors (TFs) regulate the gene expression of their target genes by binding to the regulatory sequences of target genes (e.g., promoters and enhancers). To fully understand gene regulatory mechanisms, it is crucial to decipher the relationships between TFs and DNA sequences. Moreove...
(DNase-I and Tn5, respectively), which recognize and cleave DNA in open chromatin regions. Sequencing and the alignment of reads from these fragments allows the detection of open chromatin by identifying genomic intervals with many reads [1,2]. However, the presence of transcription factors (TFs...
Genome-wide maps of transcription factor binding sites in primary tissues can expand our understanding of genome function, transcriptional regulation, and genetic alterations that contribute to disease risk. However, almost all genome-wide studies of transcription factors have been in cell lines, and pe...
Transcriptional factor (TF)-encoding genes have been recognized as one important source of the diversity and change that underlie the evolution of plants6,7. Moreover, identification of the transcriptional factors (TF;transelements) and their cognate transcriptional factor binding-sites (TFBS;ciselement...
DNA methylation presents distinct binding sites for human transcription factors. Elife 2013 (2013). Raghav, S.K. et al. Integrative genomics identifies the corepressor SMRT as a gatekeeper of adipogenesis through the transcription factors C/EBPB and KAISO. Mol. Cell 46, 335–350 (2012). Article...
Transcription factors (TFs) are key cellular components that control gene expression. They recognize specific DNA sequences, the TF binding sites (TFBSs), and thus are targeted to specific regions of the genome where they can recruit transcriptional co-factors and/or chromatin regulators to fine-...
Human liver fatty acid binding protein (hFABP1) gene is regulated by liver-enriched transcription factors HNF3β and C/EBPα TFSEARCH and TESS programs were used to predict potential transcription factor binding sites. Two putative binding sites for the liver-enriched transcription ... YL Wu,XE...