Platelet-derived growth factor PE: Phycoerythrin PerCP: Peridinin-chlorophyll proteins PI3K: Phosphatidylinositide 3-kinase qRT-PCR: Quantitative reverse transcriptase PCR SD-4: Syndecan-4 TKI: Tyrosine kinase inhibitors TLR: Toll-Like Receptor ...
M. Transcription factor IIA derepresses TATA-binding protein (TBP)-associated factor inhibition of TBP–DNA binding. J. Biol. Chem. 273, 14293–14300 (1998). Article CAS PubMed Google Scholar Gangloff, Y. G., Romier, C., Thuault, S., Werten, S. & Davidson, I. The histone fold ...
L. et al. Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor. J. Med. Chem. 56, 1739–1747 (2013). Article CAS PubMed PubMed Central Google Scholar Scheuermann, T. H. et al. Allosteric inhibition of hypoxia inducible factor-2 with small molecules. Nat...
Its key step, Sertoli cell differentiation in the embryonic gonadal ridge, is initiated by SRY, a Y-encoded architectural transcription factor. Mutations in human SRY cause gonadal dysgenesis leading to XY female development (Swyer syndrome). Here, we have characterized an inherited mutation ...
Based on conserved domains and functions, the GRAS family was initially classified into eight different subfamilies, including SCR, SCARECROW-LIKE3 (SCL3), SHORT-ROOT (SHR), DELLA, LATERAL SUPPRESSOR (LS), LIGHT SIGNALING through INTERACTIONS LIGHT-RESPONSIVE TRANSCRIPTION FACTOR PIFs (LISCL), ...
The CCAAT binding factor can mediate interactions between CONSTANS-like proteins and DNA Plant J., 46 (2006), pp. 462-476 Google Scholar Bi et al., 1997 W. Bi, L. Wu, F. Coustry, B. de Crombrugghe, S.N. Maity DNA binding specificity of the CCAAT-binding factor CBF/NF-Y J. ...
Sun et al., 2021investigated an apple mutant that shows an enhanced skin coloration. RNA-seq revealed that a MYB90-like transcripiton factor is a putative key regulator due to substantially increased gene expression. This TF was able to bind to the promoters ofMdCHSandMdUFGT. Overexpression of...
dmd-1has a similar role—this transcription factor regulates the formation of male somatic structures like the penis papilla, sperm ducts and seminal vesicles. In addition, it is probable thatdmd-1in planarians acts cell non-autonomously to specify male germ cells and to regulate their ...
Transcription factor IID (TFIID), like SAGA, is a multi-subunit co-factor forRNApolymerase II transcription that also contains HAT activity. However, SAGA andTFIIDmake complementary contributions to gene expression in yeast[121]. Whereas TFIID is involved in the regulation of the vast majority...
Inhibition of cellular proliferation by the Wilms’ tumor suppressor WT1 is associated with suppression of insulin-like growth factor I receptor gene expression Mol Cell Biol 1995 15: 3516–3522 CAS PubMed PubMed Central Google Scholar Kim J, Prawitt D, Bardeesy N, Torban E, Vicaner C, ...