dmd-1has a similar role—this transcription factor regulates the formation of male somatic structures like the penis papilla, sperm ducts and seminal vesicles. In addition, it is probable thatdmd-1in planarians acts cell non-autonomously to specify male germ cells and to regulate their ...
L. et al. Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor. J. Med. Chem. 56, 1739–1747 (2013). Article CAS PubMed PubMed Central Google Scholar Scheuermann, T. H. et al. Allosteric inhibition of hypoxia inducible factor-2 with small molecules. Nat...
Platelet-derived growth factor PE: Phycoerythrin PerCP: Peridinin-chlorophyll proteins PI3K: Phosphatidylinositide 3-kinase qRT-PCR: Quantitative reverse transcriptase PCR SD-4: Syndecan-4 TKI: Tyrosine kinase inhibitors TLR: Toll-Like Receptor ...
Its key step, Sertoli cell differentiation in the embryonic gonadal ridge, is initiated by SRY, a Y-encoded architectural transcription factor. Mutations in human SRY cause gonadal dysgenesis leading to XY female development (Swyer syndrome). Here, we have characterized an inherited mutation ...
The CCAAT binding factor can mediate interactions between CONSTANS-like proteins and DNA Plant J., 46 (2006), pp. 462-476 Google Scholar Bi et al., 1997 W. Bi, L. Wu, F. Coustry, B. de Crombrugghe, S.N. Maity DNA binding specificity of the CCAAT-binding factor CBF/NF-Y J. ...
Transcription factor IID (TFIID), like SAGA, is a multi-subunit co-factor forRNApolymerase II transcription that also contains HAT activity. However, SAGA andTFIIDmake complementary contributions to gene expression in yeast[121]. Whereas TFIID is involved in the regulation of the vast majority...
Werten, S. et al. Crystal structure of a subcomplex of human transcription factor TFIID formed by TATA binding protein-associated factors hTAF4 (hTAFII135) and hTAF12 (hTAFII20). J. Biol. Chem. 277, 45502–45509 (2002). Article CAS PubMed Google Scholar Bhattacharya, S., Takada, S...
Transcription factor network downstream of protease activated receptors (PARs) modulating mouse bladder inflammation. BCM Immunol 8: 17, 2007.Saban R, Simpson C, Davis CA, Dozmorov I, Maier J, Fowler B, Ihnat MA, Hurst RE, Wershil BK, Saban MR: Transcription factor network downstream of ...
Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site J Biol Chem 1994 269: 12577–12582 CAS PubMed Google Scholar Reddy JC,...
Similarities in transcription factor IIIC subunits that bind to the posterior regions of internal promoters for RNA polymerase III RNA polymerase III (RNAP III) transcribes the genes for small RNAs like tRNAs, 5S rRNA, and several viral RNAs, and short interspersed repetitive elemen... S Matsutan...