Disclosed are RNA constructs which function to activate or inactivate a biological process, e.g., may be designed for attachment to a polypeptide coding region. Such RNA constructs modulate translation of a pol
Here, we show that Firre RNA expressed from the active X chromosome maintains histone H3K27me3 enrichment on the inactive X chromosome (Xi) in somatic cells. This trans-acting effect involves SUZ12, reflecting interactions between Firre RNA and components of the Polycomb repressive complexes. ...
反式作用因子通过与基因上的调控序列结合来发挥作用。这些调控序列通常位于基因的启动子区域或其他调控区域，如增强子或沉默子等。一旦反式作用因子与这些序列结合，它们就能够改变RNA聚合酶的活性，从而影响转录的效率和速率。这种结合可能是激活基因的转录，也可能是抑制转录。3. 分类和功能：反式作用因子可...
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Table 1.Previously Unstudied RegulatedTrans-Acting RNA-Controlling Factors During T Helper Cell Activationa GO term: RNA binding (GO:0003723) GeneFPKM 4sU 0 hFPKM 4sU 4 hEmpty Cell Mettl11.8722.72 Upregulated Pus71.1714.61 Rrp95.8968.34 ...
An RNA-binding protein Hfq may negatively regulate the transposition of Tn5 and Tn10 transposons by suppressing the expression of their IS50 and IS10 transposases at the post-transcriptional level13,14. The vertebrate RAGs are also restricted by trans and cis elements to inhibit their endonuclease...
顺式作用元件可以通过改变模板的总体结构,或将模板固定在细胞核内特定的位置,促进RNA聚合酶Ⅱ在DNA链上的结合和滑动,有的还可以为RNA聚合酶Ⅱ或其它一些反式作用因子进入染色质提供一种“进入位置”。 反式作用因子是指不同染色体上基因座编码的、能直接或间接地识别或结合在各顺式作 用元件8~12bp核心序列上并...
顺式作用元件可以通过改变模板的总体结构,或将模板固定在细胞核内特定的位置,促进RNA聚合酶Ⅱ在DNA链上的结合和滑动,有的还可以为RNA聚合酶Ⅱ或其它一些反式作用因子进入染色质提供一种“进入位置”。反式作用因子是指不同染色体上基因座编码的、能直接或间接地识别或结合在各顺式作用元件8～12bp核心序列上并参与...
RNA stabilityWhile long thought to represent only "junk" DNA, several recent studies support a functional role for pseudogenes. Several hundreds of pseudogenes have been reported as transcribed into RNA in a...doi:10.1007/978-1-4939-0835-6_14...
英文: A New Endogenous Small RNA in Plants——Trans-acting siRNA 中文: 植物中的一种内源小RNA——ta-siRNA 更详细... 英文: Investigation on the suppression of HBV by trans-acting HDV ribozyme in HepG2.2.15 cell 中文: HDV核酶对乙型肝炎病毒抑制作用的研究 更详细... 英文: Preliminary Funct...