Other drugs that reduce the seizure threshold. Risk of seizure may also increase in patients with epilepsy, those with a history of seizures, or in patients with a recognized risk for seizure (such as head trauma, metabolic disorders, alcohol and drug withdrawal, CNS infections). In tramadol...
in patients taking SSRIs, SNRIs, anorectic agents, tricyclic antidepressants or other tricyclic compounds (e.g., cyclobenzaprine, promethazine), or other opiate agonists; may increase the risk in those taking MAO inhibitors, antipsychotic agents, or other drugs that decrease the seizure threshold.Se...
When a decision has been made to decrease the dose or discontinue therapy in an opioid-dependent patient taking ULTRAM, there are a variety of factors that should be considered, including the dose of ULTRAM the patient has been taking, the duration of treatment, the type of pain being treated...
Tramadol increased the risk for seizure in patients taking serotonin reuptake inhibitors, tricyclic antidepressants, and opioids (Ultram PI 2006). Tra- madol ER may also increase the risk for seizure if combined with drugs that decrease seizure threshold, such as mono- amine oxidase inhibitors (...
may also increase in patients with epilepsy, those with a history of seizures or in patients with a recognized risk for seizure (such as head trauma, metabolic disorders, alcohol and drug withdrawal, CNS infections), or with concomitant use of other drugs known to reduce the seizure threshold....
The drugs i.e. Ciprofloxacin, Metronidazole, Tramadol etc. which decrease seizure threshold were withdrawn and the child recovered after treatment with Carbamazepine.Kali Prasad PattnaikSuhasini DehuryRatikanta TripathySwayam Sourav Sahoo
27 The seizure risk with tramadol may be enhanced in patients taking tricyclic antidepressants, selective serotonin reuptake inhibitors, monoamine oxidase inhibitors, neuroleptics, or other drugs that lower the seizure threshold. Furthermore, patients with epilepsy, a history of seizures, or other risk...
By itself, it can decrease the seizure threshold. When combined with SSRIs, tricyclic antidepressants, or in patients with epilepsy, the seizure threshold is further decreased. Seizures have been reported in humans receiving excessive single oral doses (700 mg) or large intravenous doses (300 mg...
Although preconditioning-induced by ultra-low doses of tramadol had no effect on the time to onset (A), it could decrease the number of tremors (B), duration of tremor (C), number of tonic-clonic seizures (D) and duration of tonic-clonic seizure (E). However, no change was observed ...
Patients were permitted to continue treatment with all other medications with the exception of monoamine oxidase inhibitors, tricyclic antidepressants, antipsychotics, selective serotonin reuptake inhibitors or other drugs that reduce seizure threshold. The two groups were similar with regard to the use of...