1.the branch of biology that deals with the principles and mechanisms of heredity and with the genetic contribution to similarities and differences among related organisms. 2.the genetic properties or constitution of an organism or group. [seegenetic,-ics; term first proposed in this sense by Bri...
Are most traits in humans Mendelian or polygenic involving multiple genes )? Many human traits are controlled by more than one gene. These traits are calledpolygenic traits. The alleles of each gene have a minor additive effect on the phenotype. There are many possible combinations of alleles, ...
In this way, HGT has been suggested to be analogous to teaching in the spread of culture in humans (Riboli- Sasco et al., 2008). Behaviours learned from teaching are similar to plasmids in the sense that transfer is costly, they frequently confer a benefit on the recipient and the ...
The hippocampus, with its complex subfields, is linked to numerous neuropsychiatric traits. While most research has focused on its global structure or a few specific subfields, a comprehensive analysis of hippocampal substructures and their genetic corre
Genetic analysis of NMR-lipoprotein fractions in humans had shown the gene PCDH10 related with LDL cholesterol34. Scientific Reports | 7:38600 | DOI: 10.1038/srep38600 2 www.nature.com/scientificreports/ Figure 1. G × G and G × E plots of highly significant effects of QTSs...
The regions under purifying selection are best predicted by phylogenetic conservation, with ∼80% of the deleterious mutations affecting neutral diversity occurring in non-exonic regions. Thus, background selection is the dominant mode of linked selection in humans, with marked effects on diversity ...
Pleiotropic effects of coat colour-associated mutations in humans, mice and other mammals. Semin. Cell Dev. Biol. 24, 576–586 (2013). Article CAS PubMed Google Scholar Do, R. et al. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat. Genet. 45...
humans57. Other examples include K3 strains which are associated with rhinoscleroma, or K24 which are associated with nosocomial infections. Both K3 and K24 are often multi-drug resistant because they acquired multiple MGEs encoding antibiotic resistance genes58,59. Hence, virulence and resistance ...
can be a powerful family-based test of linkage and, in some cases, a test of association as well as linkage. It has recently been extended in several ways; these include allowance for implementation with quantitative traits, allowance for multiple alleles, and, in the case of dichotomous ...
TFC Mackay - 《Character Concept in Evolutionary Biology》 被引量: 2272发表: 2001年 THE GENETIC ARCHITECTURE OF QUANTITATIVE TRAITS. Phenotypic variation for quantitative traits results from the segregation of alleles at multiple quantitative trait loci (QTL) with effects that are sensit... Mackay,Tr...