Costelloe SJ, Ward JM, Dalby PA: Evolutionary analysis of the TPP-dependent enzyme family. J Mol Evol 2008, 66(1):36-49.Costelloe SJ, Ward JM, Dalby PA: Evolutionary analysis of the TPP- dependent enzyme family. J Mol Evol 2008, 66:36-49....
Evolution of the TPP-dependent enzyme family The evolutionary relationships of the thiamine pyrophosphate (TPP) dependent family of enzymes was investigated by generation of a neighbor joining (NJ) ph... S Costelloe,J Ward,P Dalby 被引量: 0发表: 2007年 Gene loss in plants: Evidence from genom...
In maize, RAMOSA3 (RA3) encodes a TPP enzyme that controls maize inflorescence architecture by mediating the axillary meristems via modulation of trehalose and T6P levels [12, 33]. These reports collectively indicated that disruption of trehalose metabolism can cause pleiotropic effects, including ...
ZIKER-0284R Anti-IASPP(inhibitory member of the ASPP family) 肿瘤细胞凋亡ASPP家族的另一个成员抗体 子科生物ZIKER ZIKER-0214R Anti-ICAD(Inhibitor of Caspase-Activated Dnase ) Caspase 激活的脱氧核糖核酸酶抑制剂 子科生物ZIKER ZIKER-0018M Anti-IDE(Insulin degradation enzyme) 胰岛素降解酶抗体 子科生...
If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.其他 Aviva Systems Biology总部位于加利福尼亚州圣迭戈,在中国北京设有办公...
Therefore, effective enzyme replacement therapy for the retina in CLN2 disease will likely require direct and sustained delivery of the TPP1 protein to the retina. The use of repeated intravitreal injections for administration of therapeutic agents to the retina can be effective for treating ...
Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics Cancer Res., 67 (2007), pp. 9472-9481, 10.1158/0008-5472.Can-07-0568 View in ScopusGoogle Scholar [53] M. Nakayama, C.P. Hong, H. Oshima, E. Sakai, S.J. Kim, M. Oshima Loss of wild-...
It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the ...
TPP1 encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidifi...
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon ...