Trehalose-6-phosphate phosphatase (TPP) is an essential enzyme catalyzing trehalose synthesis, an important regulatory factor for plant development and stress response in higher plants. However, the TPP gene family in soybean has not been reported. A comprehensive analysis of t...
Description :TPP1 is a member of the sedolisin family of serine proteases. The proenzyme is activated in thelysosome by auto-proteolysis where it cleaves tripeptides from the N-termini of substrates.Mutations of TPP1 are associated with late-infantile neuronal ceroid lipofuscinosis andSpinocerebellar...
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon ...
ZIKER-0284R Anti-IASPP(inhibitory member of the ASPP family) 肿瘤细胞凋亡ASPP家族的另一个成员抗体 子科生物ZIKER ZIKER-0214R Anti-ICAD(Inhibitor of Caspase-Activated Dnase ) Caspase 激活的脱氧核糖核酸酶抑制剂 子科生物ZIKER ZIKER-0018M Anti-IDE(Insulin degradation enzyme) 胰岛素降解酶抗体 子科生...
It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the ...
In maize, RAMOSA3 (RA3) encodes a TPP enzyme that controls maize inflorescence architecture by mediating the axillary meristems via modulation of trehalose and T6P levels [12, 33]. These reports collectively indicated that disruption of trehalose metabolism can cause pleiotropic effects, including ...
General description【一般描述】 This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated...
TPP-Ⅰ is the predominant proteolytic enzyme responsible for the intracellular degradation of neuromedin B. NMB has recently been found to be a good natural substrate for rat lysosomal TPP-Ⅰ. 展开 关键词: Rat, Tripeptidyl peptidase-Ⅰ, Neuromedin B, Late-infantile neuronal ceroid lipofuscinosis,...
Finally, the absorbance of each well was detected using an enzyme-labelling instrument under 450 nm. Cell scratch assay was used to detect the effect of TPPP3 on the migration ability of OSCC cells. We drew horizontal lines on the bottom of the 6-well plate, with a distance of 0.5 to ...
Therefore, effective enzyme replacement therapy for the retina in CLN2 disease will likely require direct and sustained delivery of the TPP1 protein to the retina. The use of repeated intravitreal injections for administration of therapeutic agents to the retina can be effective for treating ...