Uremic toxins and the brain in chronic kidney diseasedoi:10.1007/s40620-024-01929-4Bossola, MaurizioPicconi, BarbaraJournal of Nephrology (JNonline)
In several of your articles about Parkinson’s, it is stated as fact that by the time one experiences the first symptoms of Parkinson’s, 60-80% of the brain cells in the Substantia Nigra area of the brain have been destroyed. If this is a medical fact then how does it stand to reas...
tox·in (tŏk′sĭn) n. 1.A poisonous substance, especially a protein, that is produced by living cells or organisms and is capable of causing disease when introduced into the body tissues but is often also capable of inducing neutralizing antibodies or antitoxins. ...
Highly toxic livers of the pufferfish Takifugu pardalis were extracted with acidic ethanol. The toxins extracted were partially purified by chromatography on Bio-Gel P-2 and then Bio-Rex 70, resulting in separation into three fractions I, II and III. Ratios of total mouse units per fraction wer...
cGMP Signalling in the Mammalian Brain: Role in Synaptic Plasticity and Behaviour The second messenger cyclic guanosine 3鈥 ,5鈥 -monophosphate (cGMP) plays a crucial role in the control of cardiovascular and gastrointestinal homeostastis, but its effects on neuronal functions are less established. ...
Traumatic brain and spinal cord injury cause a variety of symptoms that are amenable to botulinum neurotoxin (BoNT) treatment. These symptoms, spasticity; types of bladder dysfunction, movement disorders, and neuropathic pain are discussed in this chapter. The evidence-based literature on the efficacy...
The toxin has received considerable attention not only from microbiologists but also in the field of cell biology, where it has become a powerful tool to study intracellular trafficking. In this Review, we summarize the Shiga toxin family members and their structures, receptors, trafficking pathways...
but i've been feeling like you doing the same don't bring me pain now ** in my brain i ain't feeling a thing now you can feel free to give me a heartbreak now i don't think that it's just blood in my veins now i don't die alone peacefully i gave you love when you won'...
Mitochondrial electron transport chain (ETC) function is selectively reduced in multiple tissues, including brain, from patients with Parkinson's disease (PD) and Alzheimer's disease (AD). The ETC defects are specific to each illness, involve complex I in PD and complex IV in AD, are transfera...
Researchers found that a sleep regulating mechanism may also clear away toxic proteins associated with Alzheimer's in the brain.