(2013). Toxin-antitoxin systems: biology, identification, and application . Mob. Genet. Elements 3 :e26219. 10.4161/mge.26219 [ Cross Ref ]Unterholzner S.J., Poppenberger B., Rozhon W. Toxin-antitoxin systems: Biology, identification, and application. Mob Genet Elem. 2013; 3 doi: ...
Chromosomally encoded toxin-antitoxin (TA) systems are abundantly present in bacteria and archaea. They have become a hot topic in recent years, because—after many frustrating years of searching for biological functions—some are now known to play roles in persister formation. Persister cells ...
Toxin-antitoxin (TA) systems are broadly distributed, yet poorly conserved, genetic elements whose biological functions are unclear and controversial. Some TA systems may provide bacteria with immunity to infection by their ubiquitous viral predators, bacteriophages. To identify such TA systems, we searc...
英文: Characterization of Toxin-antitoxin systems in Mycobacterium tuberculosis中文: 结核枝杆菌中毒素-抗毒素系统的鉴定 英文: Potence of vaccines were tested by toxin challenge or toxin-antitoxin neutralization tests.中文: 采用免疫攻毒或中和试验方法对研制的疫苗进行效力检验,疫苗00%合格,达到《规程》规定的...
Toxin-Antitoxin (TA) systems present in bacteria and archaea are known to regulate cell growth in response to environmental stresses. However, little is known about the presence of TA systems in picocyanobacteria. This study investigated complete genomes of Synechococcus and Prochlorococcus to understand...
Toxin-Antitoxin Systems Are Abundant in Bacterial Genomes Toxin-antitoxin (TA) systems are widespread genetic modules that encode both a stable toxic protein, whose overexpression can lead to growth arrest or cell death, and a corresponding labile antitoxin, which neutralizes the toxin’s activity du...
2007. Toxin-antitoxin systems are ubiquitous and plasmid-encoded in vancomycin-resistant enterococci. Proc. Natl. Acad. Sci. USA 104:311-316.Moritz EM, Hergenrother PJ (2007) Toxin-antitoxin systems are ubiquitous and plasmid-encoded in vancomycin-resistant enterococci. Proc Natl Acad Sci USA 104...
(TA)systemsarecommoninmicroorganismsandarefrequentlyfoundinthechromosomesandlow-copynumberplasmidsofbacterialpathogens.OnesuchsystemiscarriedbythelowcopynumberplasmidpSM19035ofthepathogenicbacteriumStreptococcuspyogenes.Thisplasmidencodesanomega-epsilon-zetacassettethatensuresitsstablemaintenancebypostsegregationalkillingof...
Toxin-Antitoxin Systems as Multilevel Interaction Systems Toxin-antitoxin (TA) systems are small genetic modules usually composed of a toxin and an antitoxin counteracting the activity of the toxic protein. These ... N Goeders,L Van Melderen - 《Toxins》 被引量: 166发表: 2014年 Toxin-...
Chromosomal toxin-antitoxin (TA) systems are widespread genetic elements among bacteria, yet, despite extensive studies in the last decade, their biological importance remains ambivalent. The ability of TA-encoded toxins to affect stress tolerance when o