Chemotherapy-induced AKI was induced by an intraperitoneal injection of cisplatin (20 mg/kg). Eight-week-old wild-type and Gdf15 KO mice were treated with vehicle or CP (20 mg/kg, intraperitoneally) for 72 h (n = 4 − 5). To induce DSS-induced colitis and renal ...
Neoadjuvant chemotherapy (NACT) is the standard-of-care treatment for patients with locally advanced breast cancer (LABC), providing crucial benefits in tumor downstaging. Clinical parameters, such as molecular subtypes, influence the therapeutic impact of NACT. Moreover, severe adverse events delay ...
Medical oncologists’ views on communicating with patients about chemotherapy costs: a pilot survey. J. Clin. Oncol. 25, 233–237 (2007). PubMed Google Scholar Hunter, W. G. et al. Discussing health care expenses in the oncology clinic: analysis of cost conversations in outpatient ...
Staining intensity was assigned a score using a semi-quantitative four-category grading system: 0, no staining; 1, weak staining; 2, moderate staining; and 3, strong staining. Every core was assessed individually and the mean of three readings was calculated for every case. Tumor cell staining...
Oxaliplatin scale and National Cancer Institute-Common Toxicity Criteria in the assessment of chemotherapy-induced peripheral neuropathy. The aim of the study was to compare two different neurotoxicity scales in grading chemotherapy-induced neurotoxicity.The study sample consisted of 114 canc... AL Kauti...
Prior studies of pediatric patient reports during chemotherapy indicate the symptom burden decreased over time.1,3 Whether this is because children adapt over time, receive more intense therapies earlier, or access personalized supportive care interventions over time is an underexplored but important ...
Oxaliplatin scale and National Cancer Institute-Common Toxicity Criteria in the assessment of chemotherapy-induced peripheral neuropathy. The aim of the study was to compare two different neurotoxicity scales in grading chemotherapy-induced neurotoxicity.The study sample consisted of 114 canc... AL K...
The study evaluated the number of cases where therapy was temporarily discontinued or suspended due to AE that concerned haematological, neurological and gastrointestinal toxicity according to the CTCAE system, which provides a numerical grading scale for AE description. The prevalence of polymorphisms and...
Concomitant chemotherapy entered models for acute endpoints. Sex entered models for xerostomia and STAT scores. The protocol entered models for xerostomia, STATlate and STATglobal. Principal components were introduced stepwise in analysis and included if significant (α = 0.05). Associations ...
Also, the intensity of the pre-infusion chemotherapy correlates with the severity of neurotoxicity [113]. Diagnosis of neurotoxicity is based on clinical signs and symptoms including tremor, malaise, dizziness, confusion. disorientation, attention deficit, encephalopathy, and delirium) somnolence, ...