We identified one SJS/TEN case following new exposure to clonazepam, but the ALDEN-based causality was “very unlikely” because clonazepam was continued for more than a year after disease onset. Clonazepam was reported not as a risk factor for SJS/TEN in a previous study with a large number...
coli injection, indicating that IL-6 produced at delayed time points a few hours after exposure of endotoxin indeed exacerbates systemic inflammation. In accordance with this idea, treatment of mice with anti-IL-6R antibody at the late phase (6–8 h) of CLP prolonged the survival of mice ...
We recorded epidemiological and clinical data including age and sex of the patients, the date and time of the poisoning, the toxic substance, the type of exposure, and the clinical and biological parameters at admission to the ED. Acute poisoning is defined as adverse health effects due to ...
Another disadvantage is the short duration of the experimental setup of 120 h, as especially elements like copper seem to unfold a toxic effect only over longer exposure time. The results of the current study indicate that combinatory effects take place when more than one antibiotic is available....
Eye irritation; flammable liquid; H226; H315; H319; H335; skin irritation; specific target organ toxicity-single exposure. Eye irritation; H315; H319; H335; skin irritation; specific target organ toxicity-single exposure. Aspiration hazard; carcinogenicity; eye irritation; H225; H304; H315;...
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To our knowledge, this is the first report of the toxicity of Th to algae with its chemical species in the exposure medium. This finding provides useful information on understanding the fate and toxicity of Th in the aquatic environment. Keywords: thorium; speciation; toxicity; green algae; ...
(Zn) in the rural industrial abandoned site in North China; (2) to identify anthropogenic contamination of heavy metal in topsoil using the PLI and Igeo; (3) the RAC and a health risk assessment (HRA) were used to estimate the environmental risk and human exposure risk to PTEs in a ...
Because of its functions in filtration, transport and reabsorption, the kidney is a primary target organ of F and U toxicity; F and U exhibit renal accumulation, specifically in the cortical and juxtaglomerular areas where the proximal tubules are located [10–13]. Indeed, acute exposure to U...
2.4E´08 9.5E-10 - - - 2.3E´07 With respect to the three exposure pathways, it can be seen from Table 4 that dust ingestion is the most important for exposure to potentially toxic elements in dust, which contributes 92% and 84% of the total HQs to children and adults, ...