Predicting the total number of human genes. Nat Genet 1994;8:114.Antequera F, Bird A (1994) Predicting the total number of human genes. Nat Genet 8:114Antequera F, Bird A. Predicting the total number of human genes. Nat Genet. 1994;8:114....
expressed genesVariation in the estimates of the number of genes encoded by the human genome (28,000–120,000) attests to the difficulty of systematically identifying human genes. Sequencing of human chromosome 22 (Chr22) provided the first comprehensive, unbiased view of an entire human ...
How many genes are controlled by super-enhancers compared to the total number of genes expressed in these cells? Of the total amount of DNA in an organism's genome, 38% consists of adenine (A). What is the percentage of cytosine (C)? How much DNA is present ...
We also identified a significantly higher number of mutations in genes involved with overall genomic stability, paralleling levels of overall CNV and chromothripsis, in the cases with worse prognosis. While defining the exact role of genes involved in progression may still be needed for development ...
This paper is about the total number of individuals who are heterozygotic for a specified allele, before it is either lost or fixed. The exact distribution is found for small populations, and two limiting processes are investigated. 关键词: STATISTICAL GENETICS HETEROZYGOSITY BOREL-TANNER DISTRIBUTION...
Here, p represents the number of genetic variants in the cis-window of the gene under consideration (Supplementary Notes 3 and 5). For cis-QTL mapping, we took advantage of the approximate independence of the allelic imbalance and the total read counts in Eqs. (3) and (4), solving them...
transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation. The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and...
IL13, IL4, IL4RA, FCER1B and ADRB2 are susceptible genes of asthma and atopy. Our previous study has found gene–gene interactions on asthma between these genes in Chinese Han children. Whether the interactions begin in fetal stage, and whether these gen
Following recent studies9,16, demonstrating gene counts as important markers of cellular differentiation, we further propose to use UMI counts to study tumor behavior in human cancers. We observed strong correlations between total UMI counts and gene counts (the number of detectably expressed genes ...
(Fig.2d). The number of sequencing reads per unique microbial species did not differ significantly between DM P20 and DM P10 (adjustedp. > 0.999), however, it significantly decreased in the HC P20 (95% CI: 2.81–3.04) compared to the HC P10 (95% CI: 3.78–3.85) (Fig.2f). ...