Predicting the total number of human genes. Nat Genet 1994;8:114.Antequera F, Bird A (1994) Predicting the total number of human genes. Nat Genet 8:114Antequera F, Bird A. Predicting the total number of human genes. Nat Genet. 1994;8:114....
The inducible type I interferon (T1-IFN) cytokine system, part of the innate immune response, also plays a role in autoimmune rheumatic diseases including IIM9. The T1-IFN antiviral response is initiated when pathogen-associated molecular patterns are recognised by host pattern recognition receptors ...
select article Monitoring viruses and beta-lactam resistance genes through wastewater surveillance during a COVID-19 surge in Suwon, South Korea Research articleAbstract only Monitoring viruses and beta-lactam resistance genes through wastewater surveillance during a COVID-19 surge in Suwon, South Korea...
Comparison of 454-ESTs from Huperzia serrata and Phlegmariurus carinatus reveals putative genes involved in lycopodium alkaloid biosynthesis and developmen... Huperzine A, which belongs to the lycodine type of lycopodium alkaloids, has been used as an anti-Alzheimers disease drug candidate. Despite ...
transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation. The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and...
Genes Dev 18: 1926–1945 PubMed CAS Google Scholar Kishimoto H, Hamada K, Saunders M, Backman S, Sasaki T, Nakano T, Mak TW, Suzuki A (2003) Physiological functions of PTEN in mouse tissues. Cell Struct Funct 28: 11–21 PubMed CAS Google Scholar ...
select article Functional genomic analysis of phthalate acid ester (PAE) catabolism genes in the versatile PAE-mineralising bacterium Rhodococcus sp. 2G Research articleAbstract only Functional genomic analysis of phthalate acid ester (PAE) catabolism genes in the versatile PAE-mineralising bacterium Rhodo...
Antimicrobial resistance (AMR) in bacterial pathogens is now firmly recognized as major global health problem [1]. AMR arises as a direct consequence of antimicrobial usage (AMU) in humans and animals and resistant organisms and AMR-encoding genes are capable of crossing species barriers [2]. The...
A co-located group of genes that encode the biosynthesis and transport of a particular specialized metabolite. Gene expression The process by which a gene is transcribed into messenger RNA and translated by the ribosome into protein. Gene knockout The precise deletion or disruption of a gene to ...
5b), likely reflecting a combination of false negatives in eQTLGen and potential false positives in our analysis. Overall, we found that mixQTL achieves increased power compared to standard eQTL mapping on real data for the set of genes with sufficient total and allele-specific read counts....