VAGINAL ESTROGEN CREAMVaginal Estrogen PEssaryVaginal Estrogen TabletVaginal atrophy, a manifestation of estrogen deprivation after the menopause, could affect up to 60% of women, with a significant impact on their quality of life. It is often under-diagnosed and inadequately treated. Symptoms are ...
This study showed a 39% increased risk of recurrence in women using aromatase inhibitors and vaginal estrogen replacement [15]. However, the absence of significant impact on the mortality makes it unclear whether the small (or absent) systemic absorption by vaginal estrogen replacement, as ...
Skin lightening cream induced dermatitis and atrophy We present the case of a Malian woman who had been using skin-lightening creams for an excess of 5 years. On presentation to our clinic she had multiple areas of atrophy and striae with erythema. She had been using a topical estrogen cre....
The fat on women's thighs is more difficult to mobilize due to increased -2 adrenergic receptor activity induced by estrogen. Lipolysis can be initiated through adipocyte receptor stimulation (尾 adrenergic) or inhibition (adenosine or -2 adrenergic) or by inhibition of phosphodiesterase. Since many...
Therefore, topical DHEA may be a useful form of hormone replacement therapy in postmenopausal women, because it has estrogenic effects on the vaginal epithelium without the unwanted endometrial actions of estrogen HRT, and because it exerts an androgenic effect by stimulating bone formation (Labrie et...
All patients had tried numerous therapies including emollients, antifungal agents, astringents, estrogen ointments (adult woman), and testosterone ointments (men). Potent topical corticosteroids had been used intermittently for short courses, more often and longer in the adult patients than in the prep...
Selective Estrogen Receptor Modulators (SERMs) and Aromatase Inhibitors (AIs) currently hold an important place as adjuvant endocrine therapy for patients with early invasive or non-invasive, and/or advanced metastatic, hormone receptor-positive breast cancer. A substantial portion of the patients using...
A woman in her early 50's who had elected not to maintain estrogen levels with hormone replacement therapy sought a method of slowing the formation of fine lines which had appeared since menopause. She was put on a regimen of once-monthly, 30-second, full-face soaks in an alkanoic-warm ...
However, both oral and local (topical) estrogen therapy has significant limitations, and the hormone concentration and size of application should be restricted to reduce the risk of systemic side effects. Some women are sensitive to estrogen application and may suffer from estrogen dermatitis as a ...
Objective: Transdermal progesterone cream (PC) has become a popular alternative to hormone replacement therapy despite the lack of control trials. We designed a study to determine the effect of topical PC on the estrogen-stimulated endometrium of postmenopausal women. Method: Healthy postmenopausal ...