transdermal- through the unbroken skin; refers to medications applied directly to the skin (creams or ointments) or in time-release forms (skin patches); "transdermal estrogen"; "percutaneous absorption" percutaneous,transcutaneous,transdermic
astringents, estrogen ointments (adult woman), and testosterone ointments (men). Potent topical corticosteroids had been used intermittently for short courses, more often and longer in the adult patients than in the prepubertal girls. Anal dilatation had been performed in patient 3 (the 9-year-old...
For example, the use of UV blockers (e.g. octinoxate and zinc oxide) in combination with an MMP inhibitor for inhibiting photoaging of skin is known. Cosmetic compositions including an MMP inhibitor and a natural estrogen (e.g., 17-beta estradiol or an estrogen-like steroid) have also ...
Selective Estrogen Receptor Modulators (SERMs) and Aromatase Inhibitors (AIs) currently hold an important place as adjuvant endocrine therapy for patients with early invasive or non-invasive, and/or advanced metastatic, hormone receptor-positive breast cancer. A substantial portion of the patients using...
Estrogen may cause persistent hyperpigmentation by releasing melanocyte-activating leukotriene C4 [110]. In young women, ovarian hormones, specifically estradiol, modulate endothelin receptor B (ETRB) function and contribute to the regulation of microvascular endothelial function [111]. Orally, TXA ...
Intrinsic versus Extrinsic Aging: A Histopathological, Morphometric and Immunohistochemical Study of Estrogen Receptor β and Androgen Receptor. Skin Pharmacol. Physiol. 2016, 29, 178–189. [CrossRef] 7. Poljšak, B.; Dahmane, R.G.; Godic´, A. Intrinsic skin aging: The role of oxidative...
Vaginal Topical steroids 61, 62, 63, 64 B III-3 Increased risk for infectious complications and atrophy Topical estrogen application and antifungal prophylaxis suggested Topical tacrolimus/cyclosporine/pimecrolimus 63, 64, 65 B III-3 Burning Less well tolerated but better long-term efficacy cGVHD indi...
A woman in her early 50's who had elected not to maintain estrogen levels with hormone replacement therapy sought a method of slowing the formation of fine lines which had appeared since menopause. She was put on a regimen of once-monthly, 30-second, full-face soaks in an alkanoic-warm ...
A combined in vitro approach based on existing, validated OECD test methods is suggested to screen consumer products and mixtures for potential interaction with estrogen and androgen hormone receptors, in order to identify products that could have cumulative effects or support their safety concerning ...