Protein–protein interactionImmunoprecipitationDAVIDThe sirtuins are a family of NAD(+)-dependent deacylases with important effects on aging, cancer, and metabolism. Sirtuins exert their biological effects by catalyzing deacetylation and/or deacylation reactions in which Acyl groups are removed from ...
Protein-protein interaction is important in molecular and cellular biology for catalysis, regulation, immune response, and inhibition. Therefore, it is of interest to decipher PPI for the understanding of molecular biology events. Experimental methods such as yeast two-hybrid and biophysical (X-ray, ...
Protein–DNA Arrays as Tools for Detection of Protein–Protein Interactions by Mass Spectrometry Analysis of multiple proteinprotein interactions using microarray technology remains challenging, and site-specific immobilization of functional proteins i... L Gogolin,H Schroeder,A Itzen,... - 《Chembiochem...
Protein-ligand structure Proteins. plus 输入PDB,即可看到protein-ligand 结构 点击指定ligand下面的create pocket,即可在Pockets下拉找到对应的pocket 预测pocket: protein-ligand interaction diagram: Ligand docking LigPlot+ protein-ligand/peptide interaction diagram, 教程: MolStar 在线view structure ChimeraX 免费软...
Protein gel electrophoresis Western blotting Protein assays & analysis (protein interaction, enzyme and activity assays) Mass spectrometry Protein modification and crosslinking Your choices regarding cookies on this site We and our affiliates and vendors use cookies and similar technologies to operate our ...
Core elements of cell regulation are made up of protein-protein interaction (PPI) networks. However, many parts of the cell regulatory systems include unknown PPIs. To approach this problem, we have developed a computational method of high-throughput PPI network prediction based on all-to-all rig...
Tools for protein purification From expression to detection, your road map to better results Key upstream products Application Target Ligand or chemistry Ion exchange purification Protein charge thermofisher.com/ ionexchange Strong anion exchange thermofisher.com/sax Strong cation exchange thermofisher.com...
Spatiotemporal aspects of protein-tyrosine phosphatase (PTP) activity and interaction partners for many PTPs are elusive. We describe here an elegant and r... S Koch,I Helbing,SA Böhmer,... - 《Methods Mol Biol》 被引量: 3发表: 2016年 In Situ Proximity Ligation Assay (PLA) Analysis ...
This interaction is important for discovering drugs that ccurediseases by understanding how the mechanism of infections works. 2.10.1 STRING STRING stands for Search Tool for the Retrieval of Interacting Genes/Protein. It is a database for predicted protein-protein interactions (PPI) which is to ...
In protein- protein interactions, energy is not always equally distributed throughout the binding interface; a couple of focused areas may account for the main protein-protein interaction energy, called a hot spot, which can be the target for a small molecule protein-protein interaction inhibitor ...