This study demonstrates that human immunodeficiency virus type 1 (HIV-1) Tat protein amplifies the activity of tumor necrosis factor (TNF), a cytokine that stimulates HIV-1 replication through activation of NF-kappa B. In HeLa cells stably transfected with the HIV-1 tat gene (HeLa-tat cells)...
Electroacupuncture inhibits apoptosis of splenic lymphocytes in traumatized rats through modulation of the TNF-alpha/NF-kappa B signaling pathway 喜欢 0 阅读量: 28 作者:Chi,Meng,Wang,Kun,Guonian,Zhang,Jian,Wu,Huaxing,Li 摘要: Surgical trauma leads to a severe deterioration of 关键词:...
IL-13 Suppresses TNF-Induced Activation of Nuclear Factor-κB, Activation Protein-1, and Apoptosis The activation of N-terminal c-Jun kinase and mitogen-activated protein kinase kinase, implicated in the regulation of AP-1 and NF-kappa B, was also ... SK Manna,BB Aggarwal - 《Journal of ...
目的:通过观察肿瘤坏死因子(TNF-α)以及核转录因子κB(NF-κB)在颅脑损伤后脑组织中的表达变化,初步探讨两者在颅脑损伤后继发性脑损伤中的意义。方法:健康成年雄性SD大鼠64只,体重230-310g,随机分成对照组8只和颅脑损伤组56只,颅脑损伤组在外伤后1h、3h、6h、12h、24h、3d、7d处死,每组处死8只。取损伤灶周围的...
Tumor necrosis factor (TNF ) is a potent pro-inflammatory cytokine that plays an important role in immunity and inflammation, in the control of cell proliferation, differentiation and apoptosis. This paper presents a simulation study of the TNF mediated NF- B signaling pathway based on a system-...
Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis Signaling pathway via TNF-α/NF-κB in intestinal epithelial cells may be directly involved in colitis-associated carcino-genesis. Am J Physiol Gastrointest......
Vitamin C Suppresses TNFα-Induced NFκB Activation by Inhibiting IκBα Phosphorylation Carcamo JM, Pedraza A, Borquez-Ojeda O, Golde DW (2002) Vitamin C suppresses TNF-α-induced NF-κB activation by inhibiting I kappa B alpha phosphorylation. Biochem- istry 43:12995-13002... JM Cárcamo...
Fenofibrate induces effective apoptosis in mantle cell lymphoma by inhibiting the TNF|[alpha]||[sol]|NF-|[kappa]|B signaling axis 来自 Semantic Scholar 喜欢 0 阅读量: 45 作者:Zak, Z,Gelebart, P,Lai, R 摘要: Leukemia is one of the leading journals in hematology and oncology. It is ...
Cytokine signaling involves the participation of many adaptor proteins, including the docking protein TNF receptor-associated factor-2 (TRAF-2), which is believed to transmit the TNF-alpha signal through both the I kappa B/NF-kappa B and c-Jun N-terminal kinase (JNK)/stress-related protein ki...
Inhibition of NF-kappa B activity might contribute to the protective effect of heat shock response on TNF-alpha induced endothelial cell apoptosis. 来自 Wolters Kluwer 喜欢 0 阅读量: 47 作者:J You,Z Lin,W Xiao,M Lui,Z Luo DOI: 10.1097/00024382-199906001-00112 ...