NFkB was accumulated in cisplatin‐resistant cell lines and in cancer stem cells (CSC), and the administration of TNF‐alpha increased the CSC, suggesting that TNF‐alpha/NFkB signaling is involved in the accumulation of CSC. TNF‐alpha stimulation also increased the histone deacetylases HDAC1 ...
体外:TNF alpha (重组人源蛋白) (0, 10, 15, 20, 30, 50 ng/mL; 24, 48 h) 在 30 ng/mL 浓度,48 小时后降低 KB-C1 细胞活力,减少 pro-caspase-3,裂解的 caspase -3 在 KB-C1 和 KB-3-1 细胞中的表达[6].TNF alpha (重组人源蛋白) (10, 15 ng/mL; 24 h) 显着增加 KB-3-1 细...
TNF-α can be activated by Pathogen-Associated Molecular Patterns (PAMPs) such as bacterial or viral DNA, flagellin, or lipopolysaccharide (LPS), through the NFkB pathway. PAMPs can be recognized by Toll-like receptors (TLRs) thereby initiating a kinase cascade which phosphorylates and degrades t...
TNF-alpha increases tracheal epithelial asbestos and fiberglass binding via a NF-kB-dependent mechanism.Discusses a study which determined the effects of tumor necrosis factor-alpha on fiber binding to tracheal epithelial cells. Materials and methods; Results; Discussion....
这个还跟细胞特异性有关系。一般来说，TNF-a 能激活NF-kB，然后IL-6是NF-kB下游的基因，也被激活。
摘要: Decoctions of the dried flowers of Lonicera japonica Thunb. (Indongcho) have been utilized in folk remedies against various inflammatory diseases, and it is reported neuroprotectiv... 查看全部>>关键词:Lonicera japonica Thunb BV2 antiinflammatory activity NF-kB Akt ...
Flavonoids Isolated from Flowers of Lonicera japonica Thunb. Inhibit Inflammatory Responses in BV2 Microglial Cells by Suppressing TNF-alpha and IL-beta Through PI3K/Akt/NF-kb Signaling Pathways 来自 国家科技图书文献中心 喜欢 0 阅读量: 11 摘要: Decoctions of the dried flowers of Lonicera japoni ...
H.-C. OuC.-H. LeeElsevier LtdPhysiotherapyCheng Y-J, Ou H-C, Lee C-H. Low level laser therapy prevent endothelial cells from TNF-alpha/cycloheximide-induced apoptosis by modulating P38 MAPK/ NF-kB pathway. Physiotherapy. 2015;101(Sup 1):e236....
Conclusion Curcumin reverses palmitate-induced insulin resistance state in 3T3-L1 adipocytes through the NF-kB and JNK pathway.Shao-LingWANGandYingLIandYingWENandYan-FengSDOSBiomedical & Environmental SciencesWang, S.L.; Li, Y.; Wen, Y.; Chen, Y.F.; Na, L.X.; Li, S.T.; Sun, C.H...