TLR9-IN-1 英文名称: TLR9-IN-1 总访问: 62 国产/进口: 进口 半年访问: 36 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg 最后更新: 2025-5-19 货号: HY-148045 CAS 号: 2226366-86-3 参考报价: 4173; 204
TLR9-IN-1 CAS No. : 2226366-86-3 MCE 站:TLR9-IN-1 产品活性:TLR9-IN-1 是一种有效且选择性的 TLR9 抑制剂,对人 TLR9 的 IC50 为7 nM。TLR9-IN-1可用于研究不良免疫应答相关疾病。 研究领域:Immunology/Inflammation 作用靶点:Toll-like Receptor (TLR) In Vitro: TLR9-IN-1 (compound no.29) ...
Are Dependent upon Both TLR2 and TLR9 In Vivo 1Appledorn, Daniel MPatial, SonikaMcbride, AaronRooijen, Nico VanParameswaran, NarayananAmalfitano, AndreaGodbehere, Sarah
Here we describe a role for the innate immune-sensing molecule Toll-like receptor9 (TLR9)4, and its interaction with beclin1, in exercise-induced activation of AMPK in skeletal muscle. Mice that lack TLR9 are deficient in both exercise-induced activation of AMPK and plasma membrane localization...
The Toll-like receptor 9 (TLR9) is one of the key sentries of the host innate immune system that senses DNAs derived from microbes or damaged cells. Engagement of TLR9 in immune cells triggers the host inflammatory response to eliminate and clear invadin
correlated significantly with the degree of tumor differentiation、an advanced TNM stage and lymph node metastasis. Similar result was obtained by Western blot.Conclusions: TLR9 has a higher expression in pancreatic cancer tissues. TLR9 expression has a close relationship with pathological grades of ...
Surprisingly, we find local initiation of a CD8+ T cell response against antigen expressed in ∼20% of murine hepatocytes, independent of TLR9 or type I interferons and instead relying on IL-1 receptor 1-MyD88 signaling. Both IL-1α and IL-1β contribute to this response, which can be...
TLR9 and TLR7 agonists mediate distinct type Ⅰ IFN responses in humans and nonhuman primates in vitro and in vivo[J].{H}Journal of Leukocyte Biology,2012,(1):147-158.PUIG,M.; K.W.TOSH; L.M.SCHRAMM; L.T.GRAJKOWSKA; K.D.KIRSCHMAN; C.TAMI; J.BEREN; R.L.RABIN; D.VERTHELYI: ...
Toll样受体9(TLR9)表达与弥漫大B细胞淋巴瘤细胞起源及临床预后的相关性研究 《BMC Cancer》:Toll-like receptor 9 (TLR9) expression correlates with cell of origin and predicts clinical outcome in diffuse large B-cell lymphoma 编辑推荐: 本研究针对弥漫大B细胞淋巴瘤(DLBCL)预后分层难题,通过分析TLR9基因与...
Unlike their parental cells,THP1-Dual™, which weakly express TLR9, THP1-Dual™ hTLR9 cells are responsive to stimulation with TLR9 agonists, such as oligonucleotides containing CpG motifs (CpG ODNs). As expected, hTLR9 overexpression in THP1-Dual™ cells allows potent NF-κB and IRF re...