TLR9-IN-1 英文名称: TLR9-IN-1 总访问: 39 国产/进口: 进口 半年访问: 13 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg 最后更新: 2025-2-13 货号: HY-148045 CAS 号: 2226366-86-3 参考报价: 4173; 2045; 4500; 8000 立即询价 电话...
TLR9-IN-1 CAS No. : 2226366-86-3 MCE 站:TLR9-IN-1 产品活性:TLR9-IN-1 是一种有效且选择性的 TLR9 抑制剂,对人 TLR9 的 IC50 为7 nM。TLR9-IN-1可用于研究不良免疫应答相关疾病。 研究领域:Immunology/Inflammation 作用靶点:Toll-like Receptor (TLR) In Vitro: TLR9-IN-1 (compound no.29) ...
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correlated significantly with the degree of tumor differentiation、an advanced TNM stage and lymph node metastasis. Similar result was obtained by Western blot.Conclusions: TLR9 has a higher expression in pancreatic cancer tissues. TLR9 expression has a close relationship with pathological grades of pancr...
(49/50) in CA tissues, and 10.00%(2/20) and 20.00%(4/20) in the normal controls. The staining intensities of TLR9 and NF-κB in CA were significantly higher (+ +~+ + +) than those in normal controls(-~+). Positive expression rates ...
Unlike their parental cells, THP1-Dual™, which weakly express TLR9, THP1-Dual™ hTLR9 cells are responsive to stimulation with TLR9 agonists, such as oligonucleotides containing CpG motifs (CpG ODNs). As expected, hTLR9 overexpression in THP1-Dual™ cells allows potent NF-κB and IRF ...
HEK-Dual™ hTLR9 cells overexpress the human TLR9 gene as well as all elements important in its signaling cascade. They also feature two inducible reporter genes, allowing the concomitant study of the IRF and NF-κB pathways, by monitoring the Lucia lu
正确选择ODN类型 ODN的品质经专业的实验室检测,并发表文献 绿字部分:实验结果表明,从InvivoGen购买的CpG-C, 不同批次的产品刺激细胞并产生IgG的效果均一稳定,而从Sigma 和Coley购买的产品活性则非常不连续。 本文如有出入,请以原文出处为准:TLR9激动剂-CpG ODNs...
After successful modeling, mice were continuously administered for 48 h, and HE staining was used to observe pathological changes in intestinal tissue; ELISA was used to detect levels of tumor crossing factor-α (TNF-α), Interleukin-6 (IL-6) and IL-1β in intestinal tissue; Intestinal ...
Surprisingly, we find local initiation of a CD8+ T cell response against antigen expressed in ∼20% of murine hepatocytes, independent of TLR9 or type I interferons and instead relying on IL-1 receptor 1-MyD88 signaling. Both IL-1α and IL-1β contribute to this response, which can be...