Yet, multi-cellular eukaryotes are also composed of multiple cell types, tissues, and organs, each having different proteomes and thus potentially different folding demands. For example, HSPB1 is required for actin and myofibril assembly and its depletion specifically impairs cardiac progenitor fusion...
Given that there are examples of complete regeneration of complex structures, which persists into adult life, it would seem fruitful to compare regenerative mechanisms across animal phylogeny, and across taxa showing wide variations in regenerative competence. There are some shared features of regeneration...
Tissues and organs are complex ecosystems consisting of numerous cell types arranged in a manner that is inextricably related to function. Understanding tissue function and pathology thus requires knowledge of constituent cells and their states, extracellular matrix proteins and vasculature in the context ...
tissue composed of fibers that can contract, causing movement of an organ or part of the body Calcium salts ground substance; crystalline matrix of bone; very rigid structure ~ gives bone excellent support & protection Osteocytes bone cells Connective tissue A body tissue that provides support for...
Results: Pathological state vastly influenced the mechanical properties of the ovarian tissues. Significant alterations among elastic moduli of both cellular and non-cellular parts were observed. Mature teratoma tumors commonly composed of multiple cell types and heterogeneous ECM structure showed the widest...
‘skewered’ onto a needle array in a predefined geometry90,91,92,93. In this approach, medical grade needles are used to temporarily fix spheroids next to each other until they fuse. For example, spheroids composed of multiple cell types, including endothelial cells, smooth muscle cells and ...
Muscle is composed of the body of an organization, distributed in various tissues and organs and bones, every piece of muscle innervating muscles and nerves, nutrition muscle blood vessels, muscle separated packages, the connective tissue connects muscle and bones together to form an organ. Total ...
The brown adipocytes contain abundant mitochondria with special expression of uncoupling protein 1 (UCP1) in the inner mitochondrial membrane to take part in burning excess energy in brown adipocytes to produce heat [8]. Adipose tissues are heterogeneous and are composed of adipose stem and ...
which probably played a role in human brain evolution. The algorithm we present here allows for the examination of epigenetic changes in tissues and cell types that are absent from the palaeontological record, and therefore provides new ways to study the evolutionary impacts of epigenetic changes....
These stem cells are autologous to the donor, and they have the potential to become almost any type of cell in the adult body. Stem cells derived from therapeutic cloning applications would be useful in tissue and organ replacement applications (13). A particularly useful application for these ...