Most information on radiation effects on normal tissues and organs comes from observations during and after radiation therapy treatments. Some important organs, their tumor dose (TD) 5/5 and 50/5 values, and the effects of radiation on the tissues are explained in the chapter....
When CMV infects the host, it encounters a complex network of immune cells localized throughout various tissues and organs aimed at controlling the virus. Among them, lymphoid organs are crucial for orchestrating immune defense by acting as specialized sites where immune cells develop, differentiate,...
We found cell-specific changes occurring across multiple cell types and organs, as well as age-related changes in the cellular composition of different organs. Using single-cell transcriptomic data, we assessed cell-type-specific manifestations of different hallmarks of ageing—such as senescence3, ...
Research has discovered that many COVID-19 patients produce immune responses against their own body’s tissues or organs. A University of Birmingham-led study funded by the UK Coronavirus Immunology Consortium has found that many patients withCOVID-19produce immune responses agai...
However, the integrity of individual tissues and organs is subject to very different challenges based on size, function, internal architecture, and exposure to external insults. For instance, can dead cells simply be shed into the external milieu (skin, gut, lung, urinary tract) or do they ...
He first explained that the United States National Coastal Condition Report looks primarily at water quality all around the country, but also at sediment quality, the benthic index and the fish tissue contaminant index. 他首先解释说,《美国海岸状况报告》主要关注的是全国周围的水质,但也关注沉积物...
While, myocardial injection of cEVs or nEVs significantly decreased the expressions of IL-1β and IL-6 in mice heart tissues (Fig. 1F). H&E staining of other major organs, including the liver, spleen, lung, and kidney, also showed no obvious pathological changes among these four groups (...
Transcriptome analysis of human tissues and organs found many enriched genes in the brain and liver and relatively few in the lung and adipose tissue13. However, we found that the CGS brain had relatively few enriched proteins. This can be explained by the very low level of evolutionary ...
The Tnfrh1 (Tnfrsf23) gene is weakly imprinted in several organs and expressed at the trophoblast-decidua interface. BMC Genet 3: 11. Dao D, Frank D, Qian N, O'Keefe D, Vosatka RJ, Walsh CP et al. (1998). IMPT1, an imprinted gene similar to polyspecific transporter and multi-...
The present invention provides molecules that selectively home to various normal organs or tissues, including to lung, pancreas, skin, retina, prostate, ovary, lymph node, adrenal gland, liver or gut; and provides molecules that selectively home to tumor bearing organs or tissues, including to pan...