A mutation in the plum auxin-receptor encoded by PslAFB5, which acts as a negative regulator of auxin responses, results in inactive Pslafb5 protein causing accelerated fruit-ontogeny events associated with auxin hypersensitivity.Ethylene has long been considered the key regulator of ripening in clim...
Mechanism of bacterial interference with TLR4 signaling by Brucella TIR-domain-containing protein TcpB Upon activation of Toll-like receptors (TLRs), cytoplasmic Toll/interleukin-1 receptor (TIR) domains of the receptors undergo homo- or hetero-dimerization... MA Alaidarous,T Ve,L Casey,... -...
However, DMPO did not affect the overall TLR2MyD88 protein-protein interaction. DMPO binds to the BB-loop in the TIR-domain and dampens downstream signaling without affecting the overall TIR-MyD88 interaction. These data encourage the use of DMPO-derivatives as potential mechanism-based inhibitors...
A mutation in the plum auxin-receptor encoded by PslAFB5, which acts as a negative regulator of auxin responses, results in inactive Pslafb5 protein causing accelerated fruit-ontogeny events associated with auxin hypersensitivity. Ethylene has long been considered the key regulator of ripening in cl...