翻译 time to treatment failure 英[taim tu: ˈtri:tmənt ˈfeiljə] 美[taɪm tu ˈtritmənt ˈfeljɚ] 释义 [医]治疗失败时间 释义
治疗失败时间 time to treatment failure,TTF 定义为:由随机化开始至「退出试验」,退出原因可能是患者拒绝、疾病进展、患者死亡、不良事件等。 由于不单单展现药物疗效,因而不建议用于疗效确认性试验。 TTF 的本质是一具有综合特性的指标,所以,可造成为了达到毒性的降低,而潜在影响了预期疗效的产生。
Time to treatment failure (TTF) and overall survival (OS) with palbociclib (PAL) plus endocrine therapy (ET) versus ET in HR+/HER2- advanced breast cancer (ABC) patients: A real-world multicenter study from China.doi:10.1200/JCO.2023.41.16_suppl.e13048...
Time to treatment failure (TTF) and overall survival (OS) with palbociclib (PAL) plus endocrine therapy (ET) versus ET in HR+/HER2- advanced breast cancer ... Time to treatment failure (TTF) and overall survival (OS) with palbociclib (PAL) plus endocrine therapy (ET) versus ET in HR+...
aThe primary objective was overall survival (OS) and secondary end points included time to treatment failure (TTF) and the disease control rate (DCR). The chi-square test was used to compare the DCR in patients with and without hyponatremia. OS and TTF were estimated with the Kaplan-Meier ...
Lessons Learned. endpoint was enough time to treatment failure (TTTF) (i.e. radiological and/or symptomatic progression). The secondary endpoints included the tumor response rate (RECIST 1.0) security (National Malignancy Institute Common Terminology Criteria for Adverse Events version 3.0) quality ...
As part of a randomized clinical trial to compare theefficacy and safety of selective laser trabeculoplasty (SLT)to argon laser trabeculoplasty (ALT), we determined the differencein time to treatment failure on the one year cohort. We definedtreatment failure using three criteria: i. IOP drop...
Treatment group differences for time to discontinuation due to patient decision were attenuated after censoring the reclassified patients, but were still suggestive. Treatment comparisons for time to treatment failure were consistent with all-cause discontinuation, although somewhat smaller. All-cause ...
摘要: Objectives To develop prognostic models for time to 12-month remission and time to treatment failure after initiating antiepileptic drug monotherapy for generalised and unclassified epilepsy.关键词:Epilepsy Randomised Trials 被引量: 16 年份: 2014 ...
The primary endpoint was the time to treatment failure (TTF). Secondary endpoints included survival, remission rate, toxicity and quality of life. Results : The overall response rate was 75% in the BP and 70% in the MP group. A significantly higher number of patients treated with BP ...