Summary The syndromes of resistance to thyroid hormone (RTH) are rare disorders characterized by elevated levels of circulating free thyroid hormones, inappropriate {TSH} secretion and variably reduced peripheral tissue responses to iodothyronine action. On the basis of clinical features, two major forms...
thyroid hormone resistancethyroid hormonesWithout firm diagnosis a 16-year old boy was submitted to subtotal thyroidectomy because of a diffuse goitre and emotional instability. No definite improvement was obtained in the alleged toxic symptoms and the goitre recurred. During subsequent years ...
Thyroid hormone resistance Other types of thyroiditis (inflammation of the thyroid), such as acute thyroiditis and postpartum thyroiditis Hyperthyroidism Hyperthyroidism describes excessive production of thyroid hormone, a less common condition than hypothyroidism. Symptoms of hypothyroidism usually relate to in...
Resistance to thyroid hormone induced tachycardia in RTHalpha syndrome. Nat. Commun. 14, 3312 (2023). Article CAS PubMed PubMed Central Google Scholar Singh, B. K. & Yen, P. M. A clinician’s guide to understanding resistance to thyroid hormone due to receptor mutations in the TRalpha ...
1.Study on TRβ gene mutation in a thyroid hormone resistance syndrome family;甲状腺激素抵抗综合征一家系TRβ基因突变研究 2.Research a case of pituitary thyroid hormone resistance syndrome whose TRβexons\' gene mutation were not found.研究一例未发现TRβ(thyroid hormone receptorβ,TRβ)外显子基...
Thyroid hormone resistance syndromes. Am J Med. 1993 Apr;94(4):424-32McDermott MT, Ridgway EC. Thyroid hormone resistance syndromes. Am J Med. 1993;94:424–32. View ArticleThyroid hormone resistance syndromes. Michael T. McDermott,E.Chester Ridgway. The American Journal of Medicine . 1993...
Resistance to thyroid hormone syndrome (RTH) is an autosomal dominant or recessive genetic disease caused by mutation of either the thyroid hormone receptorβ (THR-β) gene or the thyroid hormone receptorα (THR-α) gene. RTH due to mutations of the THR-β gene (hereafter, RTH-β) is char...
Mutations in thyroid hormone receptor α1 (TRα1) cause Resistance to Thyroid Hormone α (RTHα), a disorder characterized by hypothyroidism in TRα1-expressing tissues including the heart. Surprisingly, we report that treatment of RTHα patients with th
Resistance to thyroid hormone (RTH) is a syndrome characterized by variable tissue hyporesponsiveness to thyroid hormone (TH). Mutations in both TH receptors (THRA and THRB) isoforms have been identified and manifest different phenotypes of RTH, RTH-alpha, and RTH-beta. Patients with the RTH-bet...
2. Research a case of pituitary thyroid hormone resistance syndrome whose TRβexons\' gene mutation were not found. 研究一例未发现TRβ(thyroid hormone receptorβ,TRβ)外显子基因突变的选择性垂体甲状腺激素抵抗综合征(pituitary thyroid hormone resistance syndrome,PRTH)患者及其家系情况。