Thymic dendritic cells: surface phenotype, developmental origin and function - Shortman, Wu, et al. - 1995 () Citation Context ...ociation with B7 expression might regulate T cell survival. Also, a subpopulation of murine lymphoid CD8 � splenic-derived DC has been shown to induce apoptotic...
T celldevelopmentper seis not arrested but self-tolerance governed by T cells is broken down and signs of autoimmunity arise. For example, in mice deficient for thetranscription factor RelB, the formation of the thymic medulla is markedly defective and severe autoimmune inflammation is detected in...
T cell aging, displaying decreased TCR-triggered proliferation accompanied by restricted TCR repertoire or avidity and enhanced senescence-associated secretory phenotype (SASP), is extensively studied in the aging process, which plays an immunosuppressive role and is responsible for increased susceptibility t...
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF Article26 January 2023 Toll-like receptor signaling in thymic epithelium controls monocyte-derived dendritic cell recruitment and Treg generation ArticleOpen access12 May 2020 ZG16 enh...
8, 9 The precise function of each BM-derived cell type (dendritic cells [DC], macrophages, or B cells), however, remained relatively unclear for sometime. Macrophages are probably unable to delete self-reactive thymocytes clonally10, 11 but seem instead to have scavenger functions.12 In ...
T㏕ Cell Interactions during Cytotoxic T Lymphocyte (CTL) Responses: T Cell Derived Helper Factor (Interleukin 2) as a Probe to Analyze CTL Responsiveness ... (1980b) T-T cell interactions during cytotoxic T lymphocyte (CTL) responses: Tcell derived helper factor (interleukin 2) as a probe...
Sphingosine 1-phosphate dependence in the regulation of lymphocyte trafficking to the gut epithelium It is well established that intraepithelial T lymphocytes (IELs) are derived from conventional single-positive (SP) thymocytes, as well as unconventional d... J Kunisawa,Y Kurashima,M Higuchi,... ...
Also known as: Thymic Stromal-Derived Lymphopoietin RUO: For Research Use Only. Not for use in diagnostic procedures. SKU# 14-8498 Cat. No. Size 14-8498-62 5 ug 14-8498-80 25 ug Description: Thymic Stromal Lymphopoietin (TSLP) is a member of the B cell-stimulating factor family...
The epithelial-derived cytokine thymic stromal lymphopoietin (TSLP) is important for the initiation of allergic airway inflammation through a dendritic cell-mediated T helper 2 response. To identify the factors that control TSLP expression, we examined the ability of inflammatory mediators to regulate TS...
ARTICLE https://doi.org/10.1038/s41467-020-16081-3 OPEN Toll-like receptor signaling in thymic epithelium controls monocyte-derived dendritic cell recruitment and Treg generation Matouš Vobořil1, Tomáš Brabec1, Jan Dobeš 1, Iva Šplíchalová1, Jiří Březina 1, Adéla Čepková...