[translate] asillky sillky [translate] apenetrate 击穿 [translate] aThrombin converts inactive fibrinogen into fibrin, leading to thrombus formation. 凝血酶转换不活泼的纤维蛋白原成纤维蛋白,导致血栓形成。 [translate] 英语翻译 日语翻译 韩语翻译 德语翻译 法语翻译 俄语翻译 阿拉伯语翻译 西班牙语翻译 ...
Once converted from prothrombin, thrombin converts fibrinogen to fibrin, which, in combination with platelets from the blood, forms a clot. Medical thrombin is a protein substance produced through a conversion reaction in which prothrombin of bovine origin is activated by tissue thromboplastin in the...
Thrombin converts fibrinogen to fibrin, activates platelets and several coagulation factors, and plays a central role in thrombosis and hemostasis by regulating platelet aggregation and blood coagulation. Here, we show that thrombn enhanced vascular endothelial growth factor (VEGF) production in a dose...
The first consideration is whether target fibrin-rich thrombus should be targeted versus platelet adhesion and aggregation. For example, activation of the clotting cascade with eventual activation of thrombin and conversion of fibrinogen to fibrin are critical processes in venous thrombosis and valve ...
The meaning of THROMBIN is a proteolytic enzyme that is formed from prothrombin and facilitates the clotting of blood by catalyzing conversion of fibrinogen to fibrin.
Steady-state kinetic study of the bovine thrombin-fibrinogen interaction Thrombin converts fibrinogen to fibrin monomer by hydrolyzing an Arg-Gly bond in each of the two Aa and two Bβ chains of fibrinogen. This action releases one molecule of fibrinopeptide A and one of fibrinopeptide B from...
(dysfibrinogenemia) or interfering substances (fibrin/fibrinogen degradation products, paraproteins) (Box 31.4). Some laboratories add calcium to the thrombin solution used in the TT to narrow the normal range and improve reproducibility, but this entails a loss of sensitivity to dysfibrinogens and...
It is formed from its precursor prothrombin following tissue injury and converts fibrinogen to fibrin in the final step of the clotting cascade. It also promotes numerous cellular effects including chemotaxis, proliferation, extracellular matrix turnover and release of cytokines. These actions of ...
Thrombin is serine protease involved in the coagulation cascade, which converts soluble fibrinogen into insoluble strands of fibrin - a matrix of the blood clot formation. Development of the sensitive method of the thrombin detection in nanomolar level is important for clinical practice. In this ...
the platelets in the blood first form a plug at the tear in the blood vessel. Prothrombin is converted into thrombin, its active form, which converts fibrinogen into fibrin, the tough insoluble protein that provides scaffolding and stability to theblood clot, closing the tear in the blood vess...