2003. A threshold dose-response model with random effects in teratological experiments. Commun Stat Theory Meth 32: 1439-1457Hunt D, Rai S. 2003. A threshold dose-response model with random effects in teratological experiments. Commun. Stat. Theory Methods 32: 1439-1457....
Data from a developmental toxicity study of a toxic agent were analysed, using the proposed RE threshold dose-response model, which is an extension of logit in form. Also, an approximate likelihood function was used to derive parameter estimates from this model, and tests were performed to ...
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(3) The majority of courts have rejected the monotonic, non-threshold dose response theory, requiring a plaintiff's expert instead to utilize the traditional threshold dose response concept to establish causation. The emerging battlefield: should the use of a nonmonotonic, non-threshold dose-...
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Cohen, B. L. (1981) Long-term consequences of the linear-no- threshold dose-response relationship for chemical carcinogens, Risk Analysis 1,267-275.P. D. Moskowitz etal.: “Photovoltaic Energy Technologies: Health and Envi-ronmental Effects Document,” Brookhaven National Laboratory Report BNL- ...
For non-threshold chemicals, the dose-response curve is – or is presumed to be – smoother and more uniform (constant slope), and intersects the dose-response plot at the zero point. 对于没有临界点的化学品,剂量一反应曲线比较平坦和均匀, 或据推定比较平坦和均匀(坡度稳定),并在零点上与剂量...
For non-threshold chemicals, the dose-response curve is – or is presumed to be – smoother and more uniform (constant slope), and intersects the dose-response plot at the zero point. 对于没有临界点的化学品,剂量一反应曲线比较平坦和均匀, 或据推定比较平坦和均匀(坡度稳定),并在零点上与剂量一...
Following the initial observation of a toxic effect of a substance in humans or animals (“hazard identification”), the determination of the dose-effect relationship for the observed toxic effect represents the next step. The toxicological threshold lev
- Dose-Response Vs Threshold Relationship Between Physical Activity and Function in Knee OAD. D. Dunlop