This work challenges the current reliance on "The Three R's" or Replacement, Reduction and Refinement which direct most animal research in the behavioral sciences. The author argues that these principles that were developed in the 1950's to guide the use of animals in research studies are ...
Animal research Journal editors could help raise profile of three Rs of animal research {#article-title-2} EDITOR—The RSPCA (Royal Society for the Protection of Cruelty ... British Medical Journal Publishing Group - 《Bmj Publishing Group Ltd》 被引量: 2发表: 2001年 Transparency in Non-Techn...
RS Hattori,M, Oura,T, Sakamoto,... - 《Animal Genetics》 被引量: 0发表: 2010年 Incubation Temperature and Maternal Resource Provisioning, but Not Contaminant Exposure, Shape Hatchling Phenotypes in a Species with Temperature-Dependent... The environment experienced during embryonic development is a...
Gene regulatory elements are central drivers of phenotypic variation and thus of critical importance towards understanding the genetics of complex traits. The Functional Annotation of Animal Genomes consortium was formed to collaboratively annotate the functional elements in animal genomes, starting with domes...
A. FISHER THE Department of Genetics, at Cambridge, is being organised with a view to carrying out research in the three fields of Animal, Plant and Human Genetics. The colony of mice now run for about 20 years is being reorganised, with the establishment of 21 inbred lines each ...
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), first broke out in Wuhan, China, in 2019. SARS-CoV-2 develops many types of mutations (such as B.1.1.7), making diagnosis and treatment chall
Cattle brucellosis is a severe zoonosis of worldwide distribution caused by Brucella abortus and B. melitensis. In some countries with appropriate infrastructure, animal tagging and movement control, eradication was possible through efficient diagnosis a
RS acknowledges the funding support from the Australian Research Council (Discovery Project DP120100240) and the Australian Government (Australia-China Science & Research Fund, ACSRF00980). Author information Author notes Authors and Affiliations State Key Laboratory of Veterinary Etiological Biology, Key ...
All SNPs are referred to by their ss# or rs# available in dbSNP (www.ncbi.nlm.nih.gov/SNP/). All raw data are provided in Supplementary File S1 in PLINK format, where the .ped file contains all genotypes for all individuals and all 8168 SNP markers and the .map file contains all ...
C. et al. Mind the gap: upgrading genomes with Pacific Biosciences RS long-read sequencing technology. PLoS ONE 7, e47768 (2012). Article ADS CAS PubMed PubMed Central Google Scholar Langmead, B. & Salzberg, S. L. Fast gapped-read alignment with Bowtie 2. Nat. Methods 9, 357–...