Cell proliferationThioredoxin Related Transmembrane Protein 1 (TMX1) encodes a thiol-disulfide oxidoreductase and regulates cleavage, formation, or isomerization of disulfide bonds among cysteine residues in proteins. Using bioinformatic analysis, we firstly prove TMX1 is significantly upregulated in lower-...
Identification of a Novel Thioredoxin-related Transmembrane Protein We recently identified a series of transforming growth factor-尾-responsive genes in A549 human adenocarcinoma cell line by a gene trap screening method. H... Y Matsuo,N Akiyama,H Nakamura,... - 《Journal of Biological Chemistry》...
Thioredoxin-related transmembrane protein 2 (TMX2) regulates the Ran protein gradient and importin-β-dependent nuclear cargo transportTHIOREDOXINPROTEIN transportMEMBRANE proteinsGENETIC regulationCYTOPLASMTMX2 is a thioredoxin family protein, but its functions have not been clarified. To elucidate the ...
VDUP1: vitamin D3upregulated protein-1 ASK1: apoptosis signal-regulating kinase 1 ROS: reactive oxygen species TMX: transmembrane thioredoxin-related protein ER: endoplasmic reticulum GSH: glutathione TRX: thioredoxin AIF: apoptosis-inducing factor ...
In cells experiencing such “ER stress,” intracellular signaling pathways termed the unfolded protein response (UPR) become activated. Upon detecting unfolded proteins, three ER transmembrane sensors—IRE1α, PERK, and ATF6—initiate the UPR pathways (Harding et al., 1999; Tirasophon et al., ...
TXNPx, a novel peroxiredoxin from thetrypanosomatidCrithidiafasiculata,has been identified (Montemartiniet al.,1998). The unique feature of TXNPx is its dependence on tryparedoxin, a thioredoxin-related protein found only in trypanosomatids (Gommelet al.,1997). Tryparedoxin supports the TXNPx...
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VDUP1: vitamin D3upregulated protein-1 ASK1: apoptosis signal-regulating kinase 1 ROS: reactive oxygen species TMX: transmembrane thioredoxin-related protein ER: endoplasmic reticulum GSH: glutathione TRX: thioredoxin AIF: apoptosis-inducing factor ...
This growth alteration was not due to cytotoxic effects nor related to changes in basal mitochondrial transmembrane potential (DeltaPsi(m)), reactive oxygen species production, or to other mitochondrial antioxidant components such as Trx2, peroxyredoxin-3, MnSOD, GPx1, and glutathione whose levels...
Recombinant Human Thioredoxin-related transmembrane protein 2/TMX2 英文别名: 中文名: RECOMBINANT HUMAN THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 2/TMX2 中文别名: RECOMBINANT HUMAN THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 2/TMX2 CBNumber: CB513276840 分子式: 分子量: 0 MOL File: Mol file 化学...