Thioredoxin-interacting protein (Txnip) has important functions in regulating cellular metabolism including glucose utilization; the expression of the Txnip gene is sensitive to the availability of glucose and other fuels. Here, we show that Txnip expression is down-regulated at the transcriptional level...
Thioredoxin-interacting protein (TXNIP) is a metabolic control protein that regulates cellular glucose uptake TXNIP is a member of the alpha arrestin protein superfamily and serves as a tumor suppressor gene. A well-known function of TXNIP is that it binds covalently to thioredoxin; this both inhib...
Thioredoxin-interacting protein ELISA Kit的详细说明书 检测范围:0.156-10 ng/mL 使用:本试剂仅供科研使用 保存:2-8℃ 有效期:6个月 检测方法:ELISA 产品性状:96T/48T,盒装液体 贮藏条件:2-8°C 帛科ELISA试剂盒实验原理: ELISA是以免疫学反应为基础,将抗原、牽9体的特异性反应与酶对底物的高效催化作用相结...
Ageing is a natural process in living organisms throughout their lifetime, and most elderly people suffer from ageing-associated diseases. One suggested way to tackle such diseases is to rejuvenate stem cells, which also undergo ageing. Here we report that the thioredoxin-interacting protein (TXNIP...
One such molecule is thioredoxin-interacting protein (TXNIP), also designated thioredoxin-binding protein-2 (TBP-2), a member of the 伪-arrestin family of proteins and a central regulator of glucose and lipid metabolism, involved in diabetes-associated vascular endothelial dysfunction and inflammation...
中文名称:人 硫氧还蛋白相互作用蛋白(TXNIP)ELISA试剂盒 中文同义词: 人 硫氧还蛋白相互作用蛋白(TXNIP)ELISA试剂盒 英文名称:Thioredoxin Interacting Protein ELISA Kit 英文同义词: Thioredoxin Interacting Protein ELISA Kit CAS号: 分子式: 分子量:0 EINECS号: Mol文件:Mol File 按省份浏览供应商 中国供应...
Recently, we identified thioredoxin-interacting protein (TXNIP) as a proapoptotic β-cell factor that is induced by glucose, raising the possibility that TXNIP may play a role in β-cell glucose toxicity.RESEARCH DESIGN AND METHODS—To assess the effects of glucose on TXNIP expression and ...
Numerous studies have demonstrated that thioredoxin‐interacting protein (TXNIP) expression of peripheral blood leucocytes is increased in coronary artery disease (CAD). However, the molecular mechanism of this phenomenon remained unclear. DNA methylation plays important roles in the regulation of gene ...
and small GTPases.Previously, we showed that thioredoxin-interacting protein (TXNIP, also VDUP1 [vitamin D upregulated protein 1] and TBP-2 [thioredoxin binding protein 2]) was regulated by fluid shear stress; TXNIP expression was increased in disturbed flow compared with steady flow areas. Al...
Thioredoxin-interacting protein (TXNIP) has emerged as a key regulator of important cellular processes including redox state, inflammation, and apoptosis and plays a particularly critical role in pancreatic β-cell biology and diabetes development. High glucose and diabetes induce TXNIP expression, whereas...