The role of heparin in COVID-19 infection is complex. In the form of heparan sulfate proteoglycans (HSPGs), heparin has the added benefit of being host cell surface receptors for pathologic proteins and viruses [30]. Hence, heparin is involved in “pleiotropic activity”, which is anti-infla...
This compound is highly active against Gram-negative microorganisms, with an intensity comparable to that of colistin and polymyxin B; however, it demonstrates a more extensive range of action, with some activity also against Gram-positive bacteria [29]. The use of a range of biophysical tools ...