We present three patients with COVID-19 who developed acute renal failure during hospitalization and were seen to have an improvement in their kidney function after being started on therapeutic anticoagulation with heparin (Target PTT 58鈥 93seconds) for varying indications (atrial fibrillation, ...
In addition to heparin, other drugs have been coated onto stents with certain promising results. Some of these include trials with stents coated with the chemotherapeutic agents Taxol or Paclitaxel, with the immunosuppressive agent rapamycin (a naturally occurring macrocyclic lactone which acts as an i...
E. et al. Identification of TACC1, NOV, and PTTG1 as new candidate genes associated with endocrine therapy resistance in breast cancer. J. Mol. Endocrinol. 42, 87–103 (2009). Article CAS PubMed Google Scholar McCallum, L. et al. A novel mechanism for BCR-ABL action: stimulated ...
Isolation of PBMC: human whole blood was collected in heparin tubes and PBMCs were separated by Ficoll-hypaque density gradient centrifugation (BD, SanDiego, CA). Then PBMC were separated to CD14+monocytes with corresponding magnetic beads. The CD14+monocytes differentiated to macrophage under 50 ...
The dose required to achieve target PTT at any time during TH was 7.1 +/- 1 vs 6 +/- 1 Units/kg/hr, p=0.78. Once patients were re-warmed heparin requirements were similar between groups. There was no difference in hospital or ICU length of stay, or in overall ICU and hospital ...
(JNCL), juvenile Batten disease, Santavuori-Haltia disease, Jansky-Bielschowsky disease and PTT-1 and TPP1 deficiencies; childhood ataxia related to EIF2B1, EIF2B2, EIF2B3, EIF2B4 and EIF2B5 with hypomyelination / disappearance of white matter from the central nervous system; Type 2 episodic ...
Excluding patients who received enoxaparin initially, 34/48 (70.8%) patients reached a therapeutic anti-Xa or partial thromboplastin time (PTT) levels. The median time to reach a therapeutic anti-Xa or aPTT was 5.6 (IQR 3.3-8.2) hours (Figure).#Conclusion:In patients with acute PE referred ...
The coagulation tests also showed significant changes: AT III and fibrinogen dropped (in the median −25.38% and −12.26%), and INR (international normalized ratio) and pTT (activated partial thromboplastin time) increased (5.56% and 10.27%, Figure 5). A statistically significant difference in...
The coagulation tests also showed significant changes: AT III and fibrinogen dropped (in the median −25.38% and −12.26%), and INR (international normalized ratio) and pTT (activated partial thromboplastin time) increased (5.56% and 10.27%, Figure 5). A statistically significant difference in...
Heparin and warfarin characteristics are summarized inFigure 1. As an anticoagulant, heparin and its derivatives bind to ATIII, which inactivates factor Xa and IIa, affecting the intrinsic pathway, measured as prolonged PTT. The anticoagulant activity of heparin is associated with the formation of ...