Objective: The purpose of this study was to determine the efficacy and safety of an empiric single therapeutic dose of low-molecular weight heparin (LMWH) in the time interval preceding ultrasound investigation in patients presenting to primary care physicians (PCPs) for suspicion of DVT. Methods:...
The maximum dose of enoxaparin allowed was 140 mg BID. The standard thromboprophylaxis group was allocated to receive subcutaneous unfractionated heparin (UFH) at a dose of 5000 IU TID (if weight < 120 kg) and 7500 IU TID (if weight > 120 kg) or enoxaparin at a dose of 40 mg OD (if...
(5) contraindication for the use of TXA or low molecular weight heparin; (6) perioperative use of erythropoietin, iron, antiplatelet therapy or blood transfusion; (7) preoperative diagnosis of liver disease; (8) BMI > 35; (9) flexion deformity of ≥ 30°, varus-valgus deformity of ...
141 S protein of SARS-CoV-2 can interfere with the function of complement factor H to activate complement bypass, and directly block the combination of complement factor H with heparin, leading to complement imbalance.142 In the context of COVID-19, platelets and platelet activation biomarkers ...
Conclusions: No bemiparin dose adjustments are required in elderly with preserved renal function. RI influences the PD/PK of bemiparin but doses adjustments are only recommended for patients with severe RI impairment. 展开 关键词: Pharmacodynamics Low molecular weight heparins Bemiparin Elderly ...
Efficacy and Safety of Therapeutic-Dose Heparin vs Standard Prophylactic or Intermediate-Dose Heparins for Thromboprophylaxis in High-risk Hospitalized Patients With COVID-19: The HEP-COVID Randomized Clinical Trial. JAMA Intern. Med. 2021, 181, 1612–1620. [Google Scholar] [CrossRef] INSPIRATION ...
antibodies Review Therapeutic Antibody-Like Immunoconjugates against Tissue Factor with the Potential to Treat Angiogenesis-Dependent as Well as Macrophage-Associated Human Diseases Zhiwei Hu ID Department of Surgery Division of Surgical Oncology, The James Comprehensive Cancer Center, The Ohio State ...
More importantly, therapeutic effects of REG1 can be controlled by dosage of RB007 and it is less toxic than heparin/protamine, which is also an anticoagulation/antidote pair currently available [74]. Phase II clinical trials for using REG1 in percutaneous coronary intervention for patients with ...