Background: The relationship between a daily dose of olanzapine, its serum concentration, and the genotype of young non-smoking males treated for schizophrenia or schizophreniform disorder was investigated in day-to-day clinical practice. Pharmacogenetics was also examined for the selected patien...
Despite being the most widely prescribed formulation, oral formulations possess several limitations such as low adherence, low bioavailability, high toxicity (in the case of anticancer drugs), and multiple-time administration requirements. All these limitations can be overcome by long-acting injectables....
Shertzer HG, Kendig EL, Nasrallah HA, Johansson E, Genter MB (2010) Protection from olanzapine-induced metabolic toxicity in mice by acetaminophen andtetrahydroindenoindole. Int J Obes 34:970–979 Article CAS Google Scholar Simmons DL, Chandrasekharan NV, Hu D, Roos KL, Tomsik J (2005) Co...
Method: The pharmacokinetics of two single therapeutic doses of olanzapine were determined in 11 healthy volunteers. The first dose of olanzapine (10 mg... R.,A.,Lucas,... - 《European Journal of Clinical Pharmacology》 被引量: 182发表: 1998年 Comparative efficacy and tolerability of drug...
Haematological alterations in the context of olanzapine treatment Introduction: Haematological alterations, especially in the red blood cell series, are a rare adverse effect of olanzapine treatment. A 64-year-old female ... B Serra,D Ramis,R Catalán,... - 《European Psychiatry》 被引量: 0发表...
(haloperidol, clozapine, thioridazine, pimozide, olanzapine) (Groos et al., 2018; Kobayashi et al., 2000) Ifenprodil (Kobayashi & Ikeda, 2006) Antidepressant drugs (partial antagonists)Paroxetine, milnacipran, trazodone GIRK1/2, GIRK1/4 and GIRK2 channels (Kobayashi et al., 2006b) Tipepidine...
Impact of Interferences Including Metabolite Crossreactivity on Therapeutic Drug Monitoring Results Dasgupta, Amitava 496-506 Therapeutic Drug Monitoring in Pregnancy Matsui, Doreen M. 507-511 Valproic Acid Significantly Lowers Serum Concentrations of Olanzapine-An Interaction Effect Comparable With Smoking ...
The paper presents an overview and analysis of the results of research on therapeutic ranges of concentrations and receptor occupancy, mainly D2 receptors, in the treatment with some atypical antipsychotic drugs. Amisulpride, aripiprazole, clozapine, quetiapine, olanzapine, risperidone, paliperidone, sert...
Huntington’s disease (HD) is a paradigm of a genetic neurodegenerative disorder characterized by the expansion of CAG repeats in the HTT gene. This e
Anxiety is a widespread psychological disorder affecting both humans and animals. It is a typical stress reaction; however, its longer persistence can cause severe health disorders affecting the day-to-day life activities of individuals. An intriguing facet of the anxiety-related disorder can be addr...