Dosing for Extended-release Injectable Suspension (Based on Corresponding Oral Doses):If the target oral olanzapine dose is 10 mg/day:Initial dose: 210 mg IM every 2 weeks OR 405 mg IM every 4 weeks for the first 8 weeks Maintenance dose: 150 mg IM every 2 weeks OR 300 mg IM every ...
If elect to use combined olanzapine and fluoxetine therapy for extended periods, periodically reevaluate the long-term risks and benefits for the individual patient.AdultsSchizophreniaOralInitially, 5–10 mg, usually as a single daily dose. Within several days, may increase by 5 mg daily, to a ...
However, these treatments are currently labour- and cost-intensive because patients either have to be observed for long periods of time in a clinical setting for safety reasons or they receive psychedelic-assisted therapy for several hours per dosing session. Thus, olanzapine may still be considered...
One interesting and important question arises: if an antipsychotic drug is administered to adolescent rats (35–60 days old; Andersen et al, 2000) for a certain number of days, after they become adults, will they still show an enhanced (sensitization) or decreased (tolerance) response to the...
Older adults and children, adolescents, or young adults can be at greater risk for some side effects from olanzapine/fluoxetine. Talk to your healthcare provider about your risks if you are in one of these age groups. What should I tell my healthcare provider before using olanzapine/fluoxetine...
Dosing considerations Dosage adjustments, if necessary, should be made at intervals greater than 24 hours Schizophrenia or Bipolar-Related Agitation in Adults 10 mg IM (short-acting) Consider 5-7.5 mg for geriatric patients or if circumstances warrant ...
We treated adolescent, male rats with olanzapine (Ola) on post-natal days 28-49, under dosing conditions that approximate those employed therapeutically in humans. As adults, they exhibited enhanced conditioned place preference for amphetamine, as compared to vehicle-treated rats. In the nucleus ...
Intramuscular Dosing In Special Populations A dose of 5 mg/injection should be considered for geriatric patients or when other clinical factors warrant.A lower dose of 2.5 mg/injection should be considered for patients who otherwise might be debilitated, be predisposed to hypotensive reactions, or ...
the daily dose can be adjusted in the range of 5-20 mg/day according to the individual's clinical condition. It is suggested that more than the recommended dose should be used only after appropriate clinical reassessment, and the interval between dosing and dosing should be no less than 24 ...
Our study showed a more complex relationship of olanzapine treatment to an ecologically valid food reward after a steady-state dosing duration. There were several limitations of this study. First, we did not have a placebo control group and this limits our ability to conclusively demonstrate that ...