From biology to ethics (2) - Therapeutic cloningAtlan, H
F. Loss of response to anti-TNFs: definition, epidemiology, and management. Clin. Transl. Gastroenterol. 7, e135 (2016). Article CAS PubMed PubMed Central Google Scholar Esposito, M. et al. Survival rate of antitumour necrosis factor-alpha treatments for psoriasis in routine dermatological ...
Cloning of ALL-1, the locus involved in leukemias with the t(4;11)(q21;q23), t(9;11)(p22;q23), and t(11;19) (q23;p13) chromosome translocations. Cancer Res., 51 (1991), pp. 6712-6739 View in ScopusGoogle Scholar 49 Y Gu, T Nakamura, H Alder, et al. The t(4;11) ch...
The MTT cell viability assay showed that L-lysine concentrations up to 150 mg/mL is not cytotoxic to Heka cells considering the definition in ISO 10993-570that states that any solution or item that reduces the cell viability to 70% or less has a cytotoxic potential70. Nonetheless, a L-l...
The stability of the cassettes was determined by passaging recombinant strains in the absence of antibiotic selection over an extended period and assessing the retention of the kanamycin resistance gene (SL7207/Chr-KmR). For comparison, aS. typhimurium SL7207strain containing a cloning vector encoding...
(PARs), a unique family of G-protein-coupled receptors, are widely expressed throughout the human body and play essential roles in various physiological and pathological processes. This review elucidates the biology and significance of PARs, outlining their diverse functions in health and disease, ...
A range of viruses could be genetically modified to infect and lyse tumor cells as cloning technology advanced. Viral treatment has succeeded because of our growing understanding of viral mechanisms of action, which include regulating the TME and triggering both innate and adaptive antitumor immunity ...
Molecular-cloning of human interleukin-2 carrier DNA and its expression in Escherichia-coli. Nucleic Acids Res. 1983, 11, 4307–4323. [Google Scholar] [CrossRef] Taniguchi, T.; Matsui, H.; Fujita, T.; Takaoka, C.; Kashima, N.; Yoshimoto, R.; Hamuro, J. Structure and expression of...
coli, as cloning directly into C. difficile is difficult. Then the plasmid can be transferred to Clostridium via conjugation [143]. However, it should be noted that DNA transfer to C. difficile occurs at low frequencies and varies significantly between C. difficile strains. Furthermore, the ...
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