The PRINCIPLE clinical trial, studied treating non hospitalized COVID-19 patients (outpatients) with azithromycin and results showed that azithromycin did not provide benefits in terms of reducing time to recovery or risk of hospitalization, when compared to standard COVID-19 treatment. ...
The cloning of the GABA-B receptors in 1997/1998 re- vived interest in these receptors and their potential as therapeutic targets. With the availability of molecular tools rapid progress was made in our understanding of the GABA-B system. This led to the surprising discovery that GABA-B ...
The retina is also more accessible than other areas of the central ner- vous system, thus making it a simpler model to work with and study. By utilizing the retinal model, we can greatly increase our knowl- edge of the cell death processes initiated by ischemia which lead to degeneration ...
The Five Stages of Grief model was developed by Swiss-American psychiatrist Elisabeth Kübler-Ross in her 1969 book On Death and Dying. For this reason, it is sometimes referred to as the Kübler-Ross model. The Five Stages of Grief model suggests an ind
The soul; the vital principle; the mind. Mental (relational) Intended for the care or treatment of persons affected by psychiatric disorders. Mental hospitals Psyche A cheval glass. Mental Mentally disordered; insane, mad, crazy. He is the most mental freshman I've seen yet. He went mental ...
Since the cancer stem cell concept has been widely accepted, several strategies have been proposed to attack cancer stem cells (CSC). Accordingly, stem cell markers are now preferred therapeutic targets. However, the problem of tumor specificity has not disappeared but shifted to another question: ...
The past few years, in particular, have seen significant changes in the way that we classify adipocytes and how we view adipose development and differentiation. We have new perspective on the roles played by adipocytes in a variety of homeostatic processes and on the mechanisms used by adipocytes...
In 1796, Edward Jenner (1749–1823) introduced the principle of vaccination, demonstrating that cowpox virus (CPXV) could be used to prevent smallpox infection and this quickly gained acceptance [21]. Initially, vaccination was performed with CPXV [24,25] and later VACV became the vaccine ...
The invasion properties of glioblastoma hamper a radical surgery and are responsible for its recurrence. Understanding the invasion mechanisms is thus critical to devise new therapeutic strategies. Therefore, the creation of in vitro models that enable these mechanisms to be studied represents a crucial...
The assessment and control of microbial contamination in health care facilities is presently a mandatory and vital part of strategies to prevent and control hospital-acquired infections. This study aims to assess the bioburden with two passive sampling methods (30 ventilations grids swabs and 16 elect...