et al. TRV120027, a novel β-arrestin biased ligand at the angiotensin II type I receptor, unloads the heart and maintains renal function when added to furosemide in experimental heart failure. Circ. Heart Fail. 5, 627–634 (2012). Article CAS PubMed Google Scholar Felker, G. M. et...
A role for inflammation in the development and progression of heart failure (HF) has been proposed for more than three decades. While several analyses have since demonstrated the potential involvement of several groups of cytokines and chemokines in acute and chronic HF, targeting these pathways in ...
This study was performed to compare therapeutic effects of two loop diuretics, long-acting azosemide and short-acting furosemide, using (123)I-metaiodobenzylguanidine ((123)I-MIBG) scintigraphy. METHODS AND RESULTS: Twenty-two patients with New York Heart Association class II-III heart failure ...
Moreover, AAGs uptake may also be stimulated by loop diuretics, like bumetanide and furosemide. These Dabrowski et al. Molecular Medicine (2018) 24:25 Page 9 of 15 drugs, which hyperpolarize the cell membrane, were shown to increase the influx of a cationic AAG (GTTR) through NSCCs, ...
Enhanced in vitro permeation of furosemide loaded into thermally carbonized mesoporous silicon (TCPSi) microparticles Eur. J. Pharm. Biopharm., 66 (2007), pp. 348-356 Google Scholar [394] N. Vale, E. Mäkilä, J. Salonen, P. Gomes, J. Hirvonen, H.A. Santos New times, new trends...
Small molecules (NQTrp, ClNQTrp, coumarin, furosemide, D737) that inhibit Aβ aggregation[265, 266] or remodel toxic soluble oligomers of Aβ[267] inhibit oligomer formation[268-274] (Table 3). Secretase inhibitors and modulators Since β-secretase and γ-secretase are responsible for the ...
Sulfonamide Derivatives such as Furosemide; others such as Minoxidil, Amlodipine, Doxazosin Mesylate, Felodipine, Moxonidine, Nicardipine Hydrochloride, Nifedipine, Prazosin hydrochloride, etc and Calcium Channel Blockers such as Arylalkylamines such as Bepridil, Ditiazem, Fendiline, Gallopamil, Terodiline...
The patient was initially treated with high dose furosemide, low flow oxygen; but later she needed multiple cycles of inotropes, vasopressors and combined diuretic therapy (metolazone and acetazolamide) to stabilize the clinical setting. The patient also experienced episodes of paroxysmal high ...
Therapeutic angiogenesis aims at restoring perfusion to chronically ischemic myocardial territories by using growth factors or cells, without intervening o
Finnerty, F.A.: Advantages and disadvantages of furosemide in the edematous states of pregnancy. American Journal of Obstetrics and Gynecology 105: 1022–1027(1969). PubMed Google Scholar Finnerty, F.A.: Treatment of acute hypertension in pregnancy. Obstetrics Gynecology Digest 12: 30–37 (1970...