Peripheral T-cell lymphoma (PTCL) is a rare and heterogeneous group of hematological malignancies. Compared to our knowledge of B-cell tumors, our understanding of T-cell leukemia and lymphoma remains less advanced, and a significant number of patients are diagnosed with advanced stages of the di...
At VCLS we have built our reputation in rare disease and our unique therapeutic depth with cross-functional approach give you the better chance of success. All therapeutic areas Oncology Indications include Various solid tumors/basket trials Breast cancer Prostate cancer Lung cancer: Non-Small-Cell ...
or switching to non-antibiotic bacterial killers, such as bacteriophages or bacteriocins. In this review, we discuss the current knowledge of the genomics of VRE isolates and state-of-the-art therapeutic advances against VRE infections.
IgG4-related disease was diagnosed base on the Comprehensive Diagnostic Criteria for IgG4-related disease [13]: (1) characteristic diffused swelling or masses in single or multiple organs; (2) elevated serum IgG4 level (≥ 135 mg/dl); (3) histopathologic presentation showing: (1) marked ...
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“BD9 can tune itself to the specific underlying conditions of the disease and potentially help more patients who do not respond to current therapies and improve outcomes for existing responders, thus addressing a large unmet need.” A dual-specific antibody, BD9 can hinder both thymic stromal ...
Merkel cell carcinoma (MCC) is a rare skin cancer characterized by neuroendocrine differentiation. Its carcinogenesis is based either on the integration of
The aim of this review is to present the advances in the treatment of β-thalassemia by providing an update on the established and emerging curative and “disease-modifying” (non-curative) treatments (Table 1). Table 1. Clinical trials of novel treatment in β-thalassemia. ...
In fact, tumor cells have been identified as far rostrally as the frontal lobe, highlighting the extensive nature of the disease [5]. Like other brain stem tumors, the degree of malignancy is determined by the differentiation level of the tumor cells, with low-grade tumors exhibiting higher ...
Study identifies new approach to overcome docetaxel resistance in patients with advanced prostate cancer The treatment landscape for patients with prostate cancer, especially individuals with advanced disease, has dramatically changed in recent years. However, aside from drug or hormonal therapies, other ta...