The Toll gene in Drosophila pattern formationdoi:10.1016/j.tig.2021.09.006Christiane Nuesslein Volhard
We recently found that JAK/STAT signaling in skeletal muscles is important for the immune response of Drosophila larvae against wasp infection, but it was not clear how muscles could affect the immune response. Here we show that insulin signaling is required in muscles, but not in fat body or...
PU.1 and interferon consensus sequence-binding protein regulate the myeloid expression of the human Toll-like receptor 4 gene. J. Biol. Chem. 275, 9773–9781 (2000). Article CAS PubMed Google Scholar Suzuki, M., Hisamatsu, T. & Podolsky, D. K. Gamma interferon augments the intracellular...
Following Japanese encephalitis virus (JEV) infection, Ripk3 gene expression is upregulated in primary neurons of wild-type (WT) mice, which corresponds to heightened viral titres [32]. RNA-sequencing of infected brain tissues revealed Ripk3−/− mice upregulate a number of IFN-stimulated ...
We then inspected the functions of these genes highly introgressed fromL. timidusintoL. granatensis. A Gene Ontology (GO) analysis revealed enrichment in several biological processes, including positive regulation of leukocyte-mediated immunity, macroautophagy, and spermatogenesis (Additional file1: Tables...
In the results pages for each experimentally validated shed membrane protein, a comprehensive shedding report was provided by SheddomeDB in four sections (Fig. 3), as follows: (i) In section A, the basic information such as protein name, gene symbol, organism, and extracellular region were re...
(92.76%) were annotated to the locally curated PANM-DB. A maximum of 5,512 unigenes had homologous sequences inTribolium castaneum.Gene Ontology (GO) analysis revealed a maximum of 5,174 unigenes in the Molecular function category. Further, in Kyoto Encyclopedia of Genes and Genomes (KEGG)...
Quantitative RT-PCR (q-RT-PCR) is a powerful tool that allows for the large scale analysis of small changes in gene expression. Accurate and reliable results depend on the use of stable reference genes for normalization. However, the expression of some widely used housekeeping genes can vary ...
2.8. Relationship between Gene Expression with Circulating IGF-1 The GE files derived from each sample were used for analysis of differential gene expression in leucocytes collected approximately 14 DIM using CLC Genomics Workbench V21 (Qiagen Digital Insights, Redwood City, CA, USA). Global gene ...
(EIR = 1.04). Proteins whose genes flank theFam161agene in house mouse chromosome 11 also had higher EIR (EIR = 0.84–1.02) (Fig.2d). These values suggest that theFam161agene evolved without haplotype selection and is an evolutionary hotspot. Finally, sperm proteins known to have...