The tumor microenvironment (TME) is a multifaceted and dynamic entity that exhibits high complexity in terms of cell types and interactions [5, 6]. Current studies indicate B cells are the primary effectors of humoral immunity in the TME and play a significant role in the regulation of the ...
representing 55.11% of the total. Among these, exotic fish species have established in 1518 basins, accounting for 50.69%, while translocated fishes have established in 603 basins, making up 19.33%. The top three river basins with the largest number of non-native...
Plant genome contains entire genetic information of a species, recording its evolutionary history and direction. Comprehensive understanding of plant genome evolution is important in revealing the relationships and evolutionary processes among plant species. Moreover, it reveals the genetic foundations that e...
8. Charoenpanich A, Wall ME, Tucker CJ, Andrews DM, Lalush DS, Loboa EG. Microarray analysis of human adipose-derived stem cells in three-dimensional collagen culture: osteogenesis inhibits bone morphogenic protein and Wnt signaling pathways, and cyclic tensile strain causes upregulation of proinf...
Some classes of virulence factors referred to as theListeriapathogenicity islands (LIPI) were identified as being responsible forListeriapathogenicity. The LIPI-1 (actA,hly, iap, plcB,plcC, prfA andmpl), LIPI-2 and the internalin genes (A, B, C and J) are regarded as the major classi...
Cardiac spheroids broadly refer to scaffold-free 3D aggregates of differentiated or primary adult cells [12]. In general, cardiac spheroids are formed by cardiomyocytes (CMs) alone or in combination with stromal cells in a defined ratio, giving rise to tissue-like structures [13]. Different from...
The NIR pathway can be found in all three domains of life—Archaea, Bacteria, and Eukaryota—with the well characterized AP endonucleases of Methanothermobacter thermautotrophicusΔH Mth212, E. coli endonuclease IV, and human APE1 proteins [6], [8], [13]. AP endonucleases are multifunctional...
These RCM values are significantly higher than 1, indicating that TBBPA has relatively high transplacental transfer efficiency. HBCD is a flame retardant that is applied to polystyrene foams and textiles. Commercial HBCD, which is widely used on a globally, consists largely of three diastereoisomers:...
(EN) category. We hypothesized three alternative models that could underlie differential isoform expression between brain regions: 1) multiple or all cell types change splice variants (‘Both-Cell-Types-Model’); 2) a single cell type changes splice variants (‘Single-Cell-Type-Model’); or 3...
However, despite this initiative regarding the promotion of innovative forms of teaching using digital media, three years later most teachers did not feel optimally prepared to successfully cope with the abrupt demands of implementing COVID-19-related e-learning [11,12]. What has been carried out...