This is a book about structures that shows students how to "see" structures as integral to architecture, and how knowledge of structures is the basis for understanding both the mechanical and conceptual aspects inherent to the art of building. Analyzing the structural principles behind many of the...
The structural basis of architectureEpstein, H ISandacker, Bjorn Normann, Eggen, Arne Petter and Mark Cruvellier. The Structural Basis of Architecture. New York: Routledge, 2011.
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The final structural concept defined in the EDM is that of an EntityContainer, which defines a closure around the sets of instances and relationships previously described. These simple concepts, used together, allow developers to define a domain model that can be mapped back to the persistence...
E. et al. Molecular architecture of the αβ T cell receptor–CD3 complex. Proc. Natl Acad. Sci. USA 111, 17576–17581 (2014). Article ADS CAS PubMed PubMed Central Google Scholar Natarajan, A. et al. Structural model of the extracellular assembly of the TCR–CD3 complex. Cell Rep....
Visual Studio, code-named "Orcas." The data to be queried can take the form of XML (LINQ to XML), databases (LINQ-enabled ADO.NET, which includes LINQ to SQL, LINQ to Dataset and LINQ to Entities), objects (LINQ to Objects), and so on. The LINQ architecture ...
The Cullin 5 (CUL5) Ring E3 ligase uses adaptors Elongins B and C (ELOB/C) to bind different SOCS-box-containing substrate receptors, determining the substrate specificity of the ligase. The 18-member ankyrin and SOCS box (ASB) family is the largest subs
2. Different types of studies in AD genetics 3. Vascular risk factors and Alzheimer's disease 4. Possible role of homozygosity and recessive cases 5. The next steps Disclosure statement Acknowledgements ReferencesShow full outline Cited by (200) Figures (2) Tables (2) Table 1 Table 2Neurobiol...
Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates. Cell 184, 370–383 (2021). Article CAS PubMed Google Scholar Pettersen, E. F. et al. UCSF Chimera—a visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605–1612...
The genetic architecture of common diseases is central to the scientific and clinical goals of human genetics because it directly impacts biology, disease screening, diagnosis, prognosis and treatment. Genetic architecture is currently assessed by exploiting the differences in types of genetic variants asc...