Retinoic acid-induced differentia- tion increases the rate of oxygen consumption and enhances the spare respiratory capacity of mito- chondria in SH-SY5Y cells. Mechanisms of ageing and development. 2012; 133(4):176-85. doi: 10. 1016/j.mad.2012.01.008 PMID: 22336883; PubMed Central PMCID: ...
3c). Baseline OCR was significantly higher in Gal-CC compared to Gluc-CC, and both the maximal respiration and the spare respiratory capacity (SRC) significantly increased in Gal-CC compared to Gluc-CC (Fig. 3c, d), indicating increased OXPHOS. Proton leak was also significantly higher in ...
infected mice.gAnalyzes of oxygen consumption rate (OCR) and spare respiratory capacity (SRC) of Tpex (n = 9 mice) and Tex cells (n = 4 mice) using a Seahorse extracellular flux analyzer; means ± SEM.hAnalysis of mitochondrial content in Tpex and Tex cells using LCMVCL13...
This increase was evident irrespectively of protein normalization and the presence or absence of fetal calf serum (FCS) but did not change the spare respiratory capacity (data not shown). Butyrate also increased glycolysis of in-vitro-activated T cells, as measured by extracellular acidification ...
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A better predictor of functional disability in patients could be the spare respiratory capacity that rapidly increased with a greater disability [96]. Obesity Obesity represents a risk factor for chronic kidney disease. In obese patients, the urinary mtDNA copy number of nicotinamide adenine ...
The New York Times reported the individual, who was hospitalized with respiratory symptoms, is from southwestern Louisiana. They came in contact with sick and dead birds; the CDC found that the viruses collected were closely related to those found in wild birds and poultry in Louisiana late in ...
capacity, or the value of lifetime experience. Today, chronological age still sustains narrow norms for living and behaviour and takes no account of the fact that people age differently in terms of their abilities.There is ,however, a difference between chronological age and biological age, and ...
(Fig.3a). Importantly, in IFN-High CD8+T cells the spare respiratory capacity (SRC), that reflects the cell ability to adapt to increased energy demand, was significantly reduced (Fig.3a). The decrease in SRC was accompanied by some reduction of intracellular ATP level (Supplementary Fig.9a...
(3.0 μM and 1.5 μM to HepG2 and RAW264.7 cells, respectively) to assess the effects of the Mtb ETC drugs on ATP turnover in these cell lines. Next, FCCP (final concentration of 1.5 μM) was added to determine the effect spare respiratory capacity. Finally, rotenone and ...