, a gene encoding the rage receptor was found specifically expressed in patients with basal type breast cancer 20 . our data suggest that padi4 inhibition or rage signaling blockade provides alternative therapeutic options for tnbc that currently lacks effective treatments. the significance of nuclear ...
Noun1.apoptosis- a type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival caspase-mediated cell death,programmed cell death ...
To evaluate the pathological significance of the pro-metastatic activity of PRAK in human cancer, we first analyzed PRAK expression in a cohort of 60-non-small cell lung cancer (NSCLC) samples, which were subgrouped according to whether distant metastasis occurred within 5 years after surgical rem...
Apoptosis refers to the genetically controlled, orderly death of cells to maintain the stability of the internal environment. Targeting certain key proteins in the apoptosis pathway is an effective approach to treat cancer and other diseases that originate from dysregulation of the apoptotic process. T...
et al. AKAP12 expression in HER2-positive breast cancer and its clinical significance. Cancer Research on Prevention and Treatment, 2020, 47(6): 441-445. doi:10.3971/j.issn.1000-8578.2020.20.0040 18. Lyu, L., Xiang, W., Zhu, J.-Y. et al. Integrative analysis of the lncRNA-...
FasL −844T/C and Fas −1377G/A: mutations of pulmonary adeno carcinoma in South China and their clinical significances Tumor Biol, 36 (2015), pp. 4319-4326 CrossrefView in ScopusGoogle Scholar [6] M. Hashemi, A. Fazaeli, S. Ghavami, E. Eskandari-Nasab, F. Arbabi, M. Mashhad...
One-way analysis of variance with SPSS 19.0 software (SPSS Inc., Chicago, IL, USA) was used for statistical test with the significance level of P < 0.05. All the specific primers were listed in Table S1. 2.6 The mRNA expression of MMPs under HS The mRNA expression profiles of four ...
Understanding the adaptive significance of the apoptotic response has the potential to create new approaches for controlling HLB. Similar content being viewed by others Asian citrus psyllid adults inoculate huanglongbing bacterium more efficiently than nymphs when this bacterium is acquired by early instar ...
Bar colors indicate the significance of the enrichment (−log10) in a hypergeometric test for the number of regulated genes. Enrichments with p-values < 5e–10 are labeled with an asterisk (p-valInmature_neuron = 4.82e–17; p-valCA1_Pyramidal = 2.59e–101; p-valS1_...
All experiments were performed in at least three independent biological replicates and reported as the mean ± the standard error of the mean. The statistical significance was calculated utilizing an unpaired two-tailed Student’s t test for direct comparisons and ANOVA for multigroup comparisons...