, a gene encoding the rage receptor was found specifically expressed in patients with basal type breast cancer 20 . our data suggest that padi4 inhibition or rage signaling blockade provides alternative therapeutic options for tnbc that currently lacks effective treatments. the significance of nuclear ...
Noun1.apoptosis- a type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival caspase-mediated cell death,programmed cell death ...
To evaluate the pathological significance of the pro-metastatic activity of PRAK in human cancer, we first analyzed PRAK expression in a cohort of 60-non-small cell lung cancer (NSCLC) samples, which were subgrouped according to whether distant metastasis occurred within 5 years after surgical rem...
including cancer stem cells. This suggests that the role of the piRNA-PIWI axis extends beyond germ cells. The expanding body of evidence underscores the significance of the
etc. has promoted the synergistic and rapid development of basic scientific research and economic industry. Identifying the frontiers of life sciences and gaining insight into the trends of innovation transformation are of great practical significance to emerging biotech companies in terms of strategic pla...
This was supported by BBB-impairing effects of osteopontin in vitro. The clinical significance of these findings is that anti-osteopontin antibody therapy might augment current approved reperfusion therapies in acute ischemic stroke by minimizing deleterious effects of ischemia-induced BBB disruption. ...
et al. AKAP12 expression in HER2-positive breast cancer and its clinical significance. Cancer Research on Prevention and Treatment, 2020, 47(6): 441-445. doi:10.3971/j.issn.1000-8578.2020.20.0040 18. Lyu, L., Xiang, W., Zhu, J.-Y. et al. Integrative analysis of the lncRNA-...
Significance: Cancer is daunting in the breadth and scope of its diversity, spanning genetics, cell and tissue biology, pathology, and response to therapy. Ever more powerful experimental and computational tools and technologies are providing an avalanche of “big data” about the myriad manifestations...
Understanding the adaptive significance of the apoptotic response has the potential to create new approaches for controlling HLB. Similar content being viewed by others Asian citrus psyllid adults inoculate huanglongbing bacterium more efficiently than nymphs when this bacterium is acquired by early instar ...
Characteristics and biological significance of ferroptosis are studied broadly and fast. Targeting or inducing the ferroptosis of cancer cells has been treated as a novel therapeutic method [151,152]. In the MYCN-amplified neuroblastoma, the iron flux was increased and the growth of cancer cells is...