Reactive oxygen species (ROS) produced during cell damage originate from different sources and play different roles. Here, we explored the potential sources of ROS production and investigated the role of ROS from various sources in oxalate-induced oxidative stress and cell inju...
Reactive oxygen species (ROS) can be generated by a variety of sources. The best known source is ionizing radiation which causes formation of hydroxyl radicals (·OH), and in the presence of O2, also superoxide anion radicals (·O-2) and hydrogen peroxide (H2O2) (Scholes, 1983). Cellular ...
Oxidative stress has been proposed to play a role in the pathogenesis of retinopathy of prematurity (ROP) for years, because of the effects of changing oxygen concentrations that occur in the preterm infant on reactive oxygen species (ROS) generation, the reduced antioxidant reserve in the preterm...
International Journal of Molecular Sciences Review The Role of Reactive Oxygen Species in Acute Myeloid Leukaemia Jonathan R. Sillar 1,2,3,*, Zacary P. Germon 2,3 , Geoffry N. De Iuliis 4 and Matthew D. Dun 2,3,* 1 Haematology Department, Calvary Mater Hospital, ...
The Role of Reactive Oxygen Species in Immunopathogenesis of Rheumatoid Arthritis Abbas Mirshafiey,Monireh Mohsenzadegan Keywords: CIA , Immunopathogenesis , Rheumatoid Arthritis , ROS Full-Text Cite this paper Add to My Lib Abstract: Rheumatoid arthritis is a disease associated with painful joints...
The Role of Neutrophil Extracellular Traps in the Outcome of Malignant Epitheliomas: Significance of CA215 Involvement REACTIVE oxygen speciesNeutrophil extracellular traps (NETs) were originally discovered as a part of the innate immune response of the host to bacteria. ... ME Himcinschi,V Uscate...
of cell death mechanisms. It has also been shown that as a consequence of ethanol metabolism, oxidative stress is induced in hepatocytes through the generation of reactive oxygen species (ROS). However, the relationship between hepatocellular oxidative stress and the promotion of cell injury is not...
The role of reactive oxygen species in the mechanisms of local and remote myocardial ischemic preconditioningThe role of reactive oxygen species in the mechanisms of local and remote myocardial ischemic preconditioningReperfusion of ischemic myocardium is accompanied by the formation of high concentrations ...
Under normal conditions, the cardiomyocyte response to acute β-adrenergic stimulation partly depends on increased production of reactive oxygen species (ROS). Here we investigated the interplay between beta-adrenergic signaling, ROS and cardiac contractility using freshly isolated cardiomyocytes and whole ...
This paper examines the hypothesis that reactive oxygen species (ROS) play an important role as second messengers in T cell activation. Activation of T cells with phorbol ester in combination with either calcium ionophore, or anti-CD3 antibody results in a large rapid flux of ROS activity. In ...