Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases (NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β-cells and/or peripheral insulin resistance, resulting in impaired glucose and lipid metabolism. Genetic, metabolic, multiple lifesty...
SINCE Hirsch's1 theory of the Golgi presubstance, according to which there exist homogeneous granular mass as a precursor of the ‘Golgi’ system, there has been very little attempt to investigate the origin of these inclusions in the cell. Nath and Chopra2 reported the origin of ‘Golgi dict...
About lipid metabolism in Hermetia illucens (L. 1758): on the origin of fatty acids in prepupaeZoologyEntomologyAlthough increasingly targeted in animal nutrition, black soldier fly larvae or prepupae (BSF,L. 1758) require the characterization and modulation of their fatty acid profile to become ...
Glycosphingolipid synthesis and tumorigenesis. A role for the Golgi apparatus in the origin of specific receptor molecules of the mammalian cell surface W. ( 1975 ) Glycosphingolipid synthesis and tumorigenesis: A role for the Golgi apparatus in the origin of specific receptor molecules of the...
amyloid origin of life Given the fact that a protein of 100 amino acids in length can contain one of 20100 possible sequences, it is evident that only an infinitesimally small part of sequence space is utilized by life or could even have been screened by life. Amyloidogenic sequences are ...
The pleiotropic phenotypes oftolmutants have obscured past efforts to define the role of Tol in the cell envelope, explaining why several functions have previously been ascribed to this trans-envelope assembly19,20. Through a multidisciplinary approach, we now define the molecular mode of action of...
Photosynthesis is generally recognized to be a primary physiology process in converting light energy into chemical energy that used for carbohydrate synthesis (Brestic et al., 2015). It has been widely accepted that leaf photosynthetic efficiency has a deterministic role in plant growth and crop prod...
of plant genome assemblies at the chromosome level [1,2,3,4]. The high-quality reference genomes and relevant phylogenomic analysis have strongly helped in identifying the plant genome organization properties, enhanced the knowledge of plant evolution, and greatly enriched the tree of life. ...
Similar phylogenetic placement was indicated for LipA and LipB nucleotide and protein sequences. The Trinidad strains also demonstrated lipolytic activity in culture, with an ability to utilize different carbon sources. Comparative evolution of MEL BGC and LipA gene suggested early and late duplication...
The role of lipid membranes in life's origin. Life (Basel). 7:E5. https://doi.org/10.3390/life7010005Deamer, D. The role of lipid membranes in life's origin. Life 7, 5 (2017).Deamer, D., 2017. The role of lipid membranes in Life's origin. Life. Biology(...