Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases (NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β-cells and/or peripheral insulin resistance, resulting in impaired glucose and lipid metabolism. Genetic, metabolic, multiple lifesty...
A substance capable of inducing free fatty acid release was sought in the blood of pregnant women. The rat epididymal fat pad was used for bioassay. Sera from 12 of 13 pregnant patients studied revealed such activity when compared to sera obtained 3 to 5 days postpartum. Serum from one pati...
About lipid metabolism in Hermetia illucens (L. 1758): on the origin of fatty acids in prepupaeZoologyEntomologyAlthough increasingly targeted in animal nutrition, black soldier fly larvae or prepupae (BSF,L. 1758) require the characterization and modulation of their fatty acid profile to become ...
Similar phylogenetic placement was indicated for LipA and LipB nucleotide and protein sequences. The Trinidad strains also demonstrated lipolytic activity in culture, with an ability to utilize different carbon sources. Comparative evolution of MEL BGC and LipA gene suggested early and late duplication...
The pleiotropic phenotypes oftolmutants have obscured past efforts to define the role of Tol in the cell envelope, explaining why several functions have previously been ascribed to this trans-envelope assembly19,20. Through a multidisciplinary approach, we now define the molecular mode of action of...
Photosynthesis is generally recognized to be a primary physiology process in converting light energy into chemical energy that used for carbohydrate synthesis (Brestic et al., 2015). It has been widely accepted that leaf photosynthetic efficiency has a deterministic role in plant growth and crop prod...
The role of lipid membranes in life's origin. Life (Basel). 7:E5. https://doi.org/10.3390/life7010005Deamer, D., 2017. The role of lipid membranes in Life's origin. Life (Basel) 7 (1).Deamer, D. The Role of Lipid Membranes in Life's Origin. Life 7, (...
2.1. The Role of Silver Nanoparticles in the Diagnosis of Cancer Personalized cancer medicine provides enormous promise for theranostics combined with diagnosis and treatment on a single nanoplatform [30,31,32]. In contrast, traditional theranostic nanoplatforms often combine therapeutic drugs with imaging...
membranes, which made the cells prone to rampant gene exchange; and that the eukaryotic supergroups emerged through distinct, secondary endosymbiotic events (as opposed to the primary, mitochondrial endosymbiosis). This biphasic model of evolution is substantially analogous to the scenario of the origin...
The Hotdog fold was initially identified in the structure of Escherichia coli FabA and subsequently in 4-hydroxybenzoyl-CoA thioesterase from Pseudomonas sp. strain CBS. Since that time structural determinations have shown a number of other apparently un