The Protein Journal is a comprehensive resource, publishing original research on all aspects of protein structure and function. Explores areas such as covalent or three-dimensional structure, assembly, genetics, evolution, proteomics, molecular biology, engineering, and peptide synthesis. ...
Protein filaments are ubiquitous in nature and have diverse biological functions. Cryo-electron microscopy (cryo-EM) enables the determination of atomic structures, even from native samples, and is capable of identifying previously unknown filament speci
Multinucleated osteoclasts, essential for skeletal remodeling in health and disease, are formed by the fusion of osteoclast precursors, where each fusion event raises their bone-resorbing activity. Here we show that the nuclear RNA chaperone, La protein
Transcription of protein-encoding genes by RNA polymerase II (pol II) to make mRNA precursors (pre-mRNAs) is the primary step in gene expression but it is not permitted to take place undisturbed in isolation within the nucleus. Well before a full-length pre-mRNA can be completed, the nascen...
Mol Biol Rep DOI 10.1007/s11033-010-0436-0 Molecular cloning and characterization of GhAPm, a gene encoding the l subunit of the clathrin-associated adaptor protein complex that is associated with cotton (Gossypium hirsutum) fiber development Tao Zhou • Rui Zhang • Dawei Yang • Sandui ...
The design of proteins that bind to a specific site on the surface of a target protein using no information other than the three-dimensional structure of the target remains a challenge1–5. Here we describe a general solution to this problem that starts
host 4 protein 0.943 protein, antigen, activation, vaccine, schistosoma 5 diagnosis 1 prevalence, diagnosis, malaria, helminth infection, plasmodium falciparum 6 schistosomiasis 1 Schistosoma mansoni, schistosomiasis, infection, mansoni, disease, bi...
protein engineering protein-protein interaction Introduction The assembly line architecture of multimodular polyketide synthases (PKSs)5 represents a promising catalytic framework for combinatorial biosynthesis (1). A particularly well studied example of this family of multienzyme systems is the 6-deoxyerythr...
The results page includes information on the sequences (including gene, CDS, and protein), functional annotations (GO, KEGG and InterPro) and the existence of homologous genes (Fig. 2b). Users can select which information should be displayed by clicking on different drop-down box options. In...
The thylakoid transit peptide of tobacco oxygen-evolving enhancer protein contains a minimal ten amino acid sequences for thylakoid lumen transports. This ten amino acids do not contain twin-arginine, which is required for typical chloroplast lumen translocation. Abstract Chloroplasts are intracellular org...