The mechanism by which Eg5 motors sort antiparallel overlaps implies that forces between microtubule pairs should strongly depend on their relative orientation15,16. In this picture, antiparallel interactions drive the motion of both filaments, whereas parallel filaments remain static16. A mean-field de...
A cytological study of the yoshida sarcoma. An ascites tumor op white rats In the Yoshida sarcoma a strain of tumor cells is present which have their own characteristic chromosome constitution and multiply by regular mitosis. The ... S Makino - 《Chromosoma》 被引量: 67发表: 1950年 Fine ...
Oncogene amplification on extrachromosomal DNA (ecDNA) is a common event, driving aggressive tumor growth, drug resistance and shorter survival. Currently, the impact of nonchromosomal oncogene inheritance—random identity by descent—is poorly understoo
which was October 25 this year. On the chance you have even a mosquito’s bunion’s amount of interest in being prepared should you encounter aHHHH, you can refresh (or
We show that in Xenopus egg extracts, which are widely used to study mitosis-specific processes, Myf5 mitotic degradation occurs through a ubiquitin- and proteasome-dependent mechanism, in a manner tightly controlled by its phosphorylation, but independent of APC/C activity. Myf5 phosphorylation is ...
A) Structure of MEF2A MADS-box/MEF2 domains bound to DNA [26] (PDB 3KOV). The MADS domain is formed by the N-terminal tail (aa 1-15 of MEF2A, in red in the picture), helix H1 (15–37, in light blue in the picture), strands β1 (41–49) and β2 (53–59). The tail...
The cytolethal distending toxin (CDT) is produced by many pathogenic Gram-negative bacteria and is considered as a virulence factor. In human cells, CDT exposure leads to a unique cytotoxicity associated with a characteristic cell distension and induces
Concurrently, DEXA up-regulates PDGFR signaling, which stimulates expression of anti-apoptotic regulators BCL2L1 and MCL1, required for survival during extended mitosis [7]. Such effects protect GBM cells and stem cells from radiotherapy-induced growth arrest, which emphasizes the controversial role of...
P.S. I haven’t written in a while due to many reasons, one of which is this pesky WordPress changed the post Editor and frankly I don’t have the time and patience to figure it out right now. But I’ll be back :). Share this: ...
of fission, ormitosis, the division of one individual into two new and identical individuals. The cells thus formed may remain clustered together to form filaments (as in many fungi) or colonies (as in staphylococci and Volvox). Fragmentation is the process in filamentous forms in which a ...