Recently, investigators have evaluated the pathophysiology of diabetes in the elderly and have found that diabetes in this age group is unique. The factors that contribute toward the high prevalence of diabetes in the aged are shown in Figure 1 ....
The Pathophysiology of Diabetes in the Elderly The pathophysiology of type 2 diabetes in younger patient populations has been extensively investigated ( 1 ). However, there have been relatively few stud... GS Meneilly 被引量: 14发表: 2007年 The Prevalence of the HNF-1α G319S Mutation in Ca...
of the B cell lymphoma 2 protein family. Our results reveal a crucial role for the miR-200 family in beta cell survival and the pathophysiology of diabetes. Access options Subscription info for Chinese customers We have a dedicated website for our Chinese customers. Please go tonaturechina.com...
The prevalence of metabolic diseases, such as obesity and type 2 diabetes (T2D), is steadily rising worldwide, due in large part to a westernized lifestyle that favors increased energy intake of highly palatable foods coupled with decreased energy expenditure. In the United States, almost three-...
pathway has been confirmed to be activated by abnormal mitochondrial function. Therefore, we can speculate that the cGAS–STING signaling pathway may participate in the pathogenesis of diabetic nephropathy, and the exploration of this mechanism may helpelucidate the pathophysiology of diabetic nephropathy....
The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes The pathophysiology of type 2 diabetes mellitus (DM) is varied and complex. However, the association of DM with obesity and inactivity indicates an importa... P Mary-Elizabeth,C Silvia - 《Endocrine Reviews》 被引量: 845...
Major: Hypertension, diabetes, advanced age, gender, and hyperlipidemia.Minor: Family history, smoking 危险因素: 最主要→高血压、糖尿病、老年、男性、高脂血症；次要→家族史、吸烟 3. What is the pathophysiology of this condition?Endothelial injury, release of growth factors, foam cells development ...
The pathogenesis of NIDDM involves a defective expression of the GIP receptor Diabetologia. 1997 Aug;40(8):984-6. JJ Holst,J Gromada,MA Nauck - 《Diabetologia》 被引量: 236发表: 1997年 Fate of the beta-cell in the pathophysiology of type 2 diabetes OBJECTIVE: To describe the progression ...
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes have been debated extensively. The concept that a feedback loop governs the interaction of the insulin-sensitive tissues and the beta cell as well as the elucidation of the hyperbolic...
International Journal of Molecular Sciences Review The Pathophysiology of Gestational Diabetes Mellitus Jasmine F Plows 1 , Joanna L Stanley 2, Philip N Baker 3, Clare M Reynolds 2 and Mark H Vickers 2,* 1 Department of Preventive Medicine, University of Southern California, Los Angeles, CA ...