If the mistake is irreparable and the rogue cell threatens to grow out of control, p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or prevented from functioning normally. Perhaps unsurprisingly, p53 is the most studied single gene in history. This ...
结果1 题目According to the passage, p53 is ___. A. a protein to prevent cancer B. a gene to defend against cancer C. a protein to destroy damaged cells D. a gene to change cells 相关知识点: 试题来源: 解析 B 反馈 收藏
All of us have lurking in our DNA a most remarkable gene, which has a crucial job - it protects us from cancer. Known simply as p53, this gene constantly scans our cells to ensure that they grow and divide without mishap, as part of the routine maintenance of our bodies. If a cell ...
Point mutations of the gene were also observed in 2 of 2 adenomas, suggesting that mutations occur prior to the carcinoma stage. These results support that p53 gene plays an important role in the development of colorectal cancer. The frequency of Ki-ras oncogene mutations was also studied by ...
P53: The Gene That Cracked the Cancer Code 类型: 精装书 作者: Armstrong, Sue ISBN13: 9781472910516 出版于: 2015-02-24 如需订购。请联系澜瑞客服获取最新的价格信息。 (因供应商数据更新原因,价格信息无法在网页上直接显示。) 合作物流商:DHL,FedEx,京东快递,顺丰快递,邮政EMS。 工作日 17:00 之前...
This book tells the story of medical science's mission to unravel the mysteries of this crucial gene, and to get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, p53: The Gene that Cracked the Cancer Code reveals the fa...
Chromosome 17p has been shown to be an early and frequent target for loss of heterozygosity through mitotic recombination in astrocytomas. These losses are frequently accompanied by point mutations in the p53 gene of the remaining allele, resulting in loss of wild type p53 function. However, a ...
- 1992 - 123 - www.sciencedirect.comdoi:10.1016/0169-5002(92)90119-5NoneLung Cancer
Soussi T. Focus on the p53 gene and cancer: Advances in TP53 mutation research. Hum Mutat 2003;21(3):173-5. (Special Issue).Soussi T: Focus on the p53 gene and cancer: advances in TP53 mutation research. Hum Mutat 21: 173-175, 2003....
The specific gene signature was obtained by averaging the expression values of all genes included in that signature to visualize in a plot single patients as each black dot and linear regression as straight blue line estimating the relationship between the two variables above mentioned. The values ...